Comparison of Intensity-and Jacobian-Based Estimates of Lung Regional Ventilation
Comparison of Intensity-and Jacobian-Based Estimates of Lung Regional Ventilation
复制标题
基于强度和雅可比行列式的肺区域通气估计值的比较
DOI：
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复制
发表时间：
2010
期刊：
影响因子：
--
通讯作者：
J. Reinhardt
中科院分区：
文献类型：
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作者：
K. Ding;K. Cao;R. Amelon;G. Christensen;M. L. Raghavan;J. Reinhardt
局部通气是在局部或区域水平上测量肺功能。肺功能的测量可以用作放射治疗（RT）规划期间的规划工具，可以用于跟踪RT期间对附近正常组织的毒性的进展，并且可以用于评估治疗后的治疗效果。在本文中，我们表明，基于强度的区域通气测量可以从雅可比的测量放松的假设，没有组织体积的变化。我们比较强度为基础的和雅可比为基础的措施，局部通风氙-CT（Xe-CT）措施的具体通风。结果表明，与基于强度的测量值（平均r = 0.54）相比，基于Jacobian的测量值与基于Xe-CT的比通气测量值的相关性更好（平均r = 0.80）。区域通气的基于强度的测量和基于雅可比的测量之间的差与扫描之间的组织体积差线性相关（平均r = 0.86）。
Regional ventilation is the measurement of pulmonary function on a local, or regional level. The measurement of pulmonary function may be useful as a planning tool during radiation therapy (RT) planning, may be useful for tracking the progression of toxicity to nearby normal tissue during RT and can be used to evaluate the effectiveness of a treatment post-therapy. In this paper, we show that an intensity-based regional ventilation measure can be derived from a Jacobian-based measure by relaxing the assumption that there is no tissue volume change. We compare intensity-based and Jacobian-based measures of regional ventilation to xenon-CT (Xe-CT) measures of specific ventilation. The results show that the Jacobian-based measure correlates better (average r = 0.80) with Xe-CT-based measures of specific ventilation than the intensity-based measure (average r = 0.54). The difference between the intensity-based measure and the Jacobian-based measure of regional ventilation is linearly related to the tissue volume difference between scans (average r = 0.86).
影响因子：
3.8
作者：
Yin, Youbing;Hoffman, Eric A.;Lin, Ching-Long
通讯作者：
Lin, Ching-Long
DOI：
10.1016/j.ijrobp.2007.01.044
发表时间：
2007-06-01
影响因子：
7
作者：
Yaremko, Brian P.;Guerrero, Thomas M.;Komaki, Ritsuko
通讯作者：
Komaki, Ritsuko
影响因子：
3.8
作者：
Ding, Kai;Bayouth, John E.;Reinhardt, Joseph M.
通讯作者：
Reinhardt, Joseph M.