Di-n-butyltin and diethyltin monofluorobenzoates: synthesis, spectroscopic characterization and in vitro antitumor activity
Di-n-butyltin and diethyltin monofluorobenzoates: synthesis, spectroscopic characterization and in vitro antitumor activity
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二正丁基锡和二乙基锡单氟苯甲酸盐：合成、光谱表征和体外抗肿瘤活性
DOI：
10.1002/aoc.590070206
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发表时间：
1993
影响因子：
3.9
通讯作者：
R. Willem,
中科院分区：
文献类型：
--
作者：
M. Gielen;A. E. Khloufi;M. Biesemans,;R. Willem,
合成了二正丁基锡(IV)和二乙基锡(IV)氟苯甲酸酯[FC6H4COO]2SnR2和(FC6H4COOR2Sn)2O并进行了光谱表征。它们对两种人类肿瘤细胞系MCF-7（乳腺肿瘤）和WiDr（结肠癌）以及NCI细胞组的体外抗肿瘤活性令人满意。
The di-n-butyltin(IV) and diethyltin(IV) fluorobenzoates [FC6H4COO]2SnR2 and (FC6H4COOR2Sn)2O have been synthesized and characterized spectroscopically. Their in vitro antitumor activity against two human tumor cell lines, MCF-7, a mammary tumor, and WiDr, a colon carcinoma, as well as against the NCI cell panel, is satisfactory.