The rewarding recovery study: a randomized controlled trial of incentives for alcohol and drug abstinence with a rural American Indian community.

The rewarding recovery study: a randomized controlled trial of incentives for alcohol and drug abstinence with a rural American Indian community.
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奖励恢复研究:一项随机对照试验的激励酒精和药物戒断与农村美国印第安人社区。

DOI:
10.1111/add.15349
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发表时间:
2021-06
期刊:
Addiction (Abingdon, England)
影响因子:
--
通讯作者:
McPherson SM
McPherson SM
中科院分区:
其他
文献类型:
--
作者:
McDonell MG;Skalisky J;Burduli E;Foote A Sr;Granbois A;Smoker K;Hirchak K;Herron J;Ries RK;Echo-Hawk A;Barbosa-Leiker C;Buchwald D;Roll J;McPherson SM

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测试是否应急管理(CM)干预酒精和药物戒断与增加酒精和药物戒断与美国印第安成年人酒精依赖谁也使用药物。在这项2x2析因随机对照试验中,美国印第安成年人酒精依赖,谁也使用药物,被随机分为四个条件:1)激励提交尿样(对照条件),2)CM激励戒酒,3)CM激励戒毒,或4)CM激励戒酒和戒毒。美国的一个北方平原保留地。114名年龄为35.8岁[10.4]的美洲印第安成年人; 51% [n=58]为女性。如果参与者通过尿检评估表明戒酒(戒酒CM,n=30)、戒酒最常用的药物(戒酒药物CM,n=27)或戒酒和戒酒最常用的药物(戒酒和戒酒药物CM,n=32),则他们将获得奖励。对照组(n=25)仅接受提交尿样的奖励。主要结果是在12周的干预期间每周进行三次尿乙基葡萄糖醛酸苷(酒精)和药物检测。数据分析包括列表删除和多重插补,以解释缺失数据。与对照组相比,三个CM组显著(p<0.05)更有可能提交戒酒尿样,比值比范围为2.4至4.8。药物组的CM和酒精和药物组的CM比酒精组的CM更有可能提交表明药物戒断的尿液样本,比值比范围为2.5至3.2,但这些差异在多重插补分析中并不显著(p> 0.05)。应急管理(CM)的禁欲激励措施与美国印第安成年人酒精依赖谁也使用药物,生活在农村保留增加戒酒。CM激励对药物戒断的影响尚无定论。
To test if contingency management (CM) interventions for alcohol and drug abstinence were associated with increased alcohol and drug abstinence among American Indian adults with alcohol dependence who also use drugs. In this 2x2 factorial randomized controlled trial, American Indian adults with alcohol dependence, who also used drugs, were randomized to four conditions: 1) incentives for submission of urine samples only (control condition), 2) CM incentives for alcohol abstinence, 3) CM incentives for drug abstinence, or 4) CM incentives for abstinence from both alcohol and drugs. A Northern Plains Reservation in the United States. 114 American Indian adults aged 35.8 years [10.4]; 51% [n=58] were female. Participants received incentives if they demonstrated abstinence from alcohol (CM for alcohol, n=30), abstinence from their most frequently used drug (CM for drugs, n=27) or abstinence from both alcohol and their most frequently used drug (CM for alcohol and drugs, n=32) as assessed by urine tests. Controls (n=25) received incentives for submitting urine samples only. Primary outcomes were urine ethyl glucuronide (alcohol) and drug tests conducted three times per week during the 12-week intervention period. Data analyses included listwise deletion and multiple imputation to account for missing data. The three CM groups were significantly (p<.05) more likely to submit alcohol abstinent urine samples compared with the control condition, with odds ratios ranging from 2.4 to 4.8. The CM for drugs and CM for alcohol and drugs groups were more likely to submit urine samples that indicated drug abstinence, with odds ratios ranging from 2.5 to 3.2, than the CM for alcohol, but these differences were not significant in multiple imputation analyses (p>.05). Contingency management (CM) incentives for abstinence were associated with increased alcohol abstinence in American Indian adults diagnosed with alcohol dependence who also used drugs, living on a rural reservation. The effect of CM incentives on drug abstinence was inconclusive.
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Hirchak KA;Leickly E;Herron J;Shaw J;Skalisky J;Dirks LG;Avey JP;McPherson S;Nepom J;Donovan D;Buchwald D;McDonell MG;HONOR Study Team
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