Evidence for fractal correlation properties in variations of peripheral arterial tone during REM sleep
Evidence for fractal correlation properties in variations of peripheral arterial tone during REM sleep
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DOI：
10.1152/ajpheart.00336.2001
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发表时间：
2002-07-01
影响因子：
4.8
通讯作者：
Lavie, P
中科院分区：
文献类型：
--
作者：
Dvir, I;Adler, Y;Lavie, P
先前利用去趋势波动分析(DFA)对睡眠期间心率变异性进行的研究显示，快速眼动(REM)睡眠时的分维指数高于非REM睡眠时的分维指数。本研究的目的是确定外周动脉张力(PAT)的变化是否存在相同的差异。用一种新的体积描记技术监测了12例慢性心力衰竭患者、8例重度鼾症患者和12名健康志愿者在睡眠中的指脉搏波。对于每个受试者，至少根据REM和非REM睡眠期间的脉搏间期和脉搏波幅构建了至少两个15分钟的时间序列。在所有组中，快速眼动睡眠时两种时间序列的分形标度指数均显著高于非快速眼动睡眠时。在每一组和两个睡眠阶段，基于脉搏波幅度的分形标度指数显著高于基于脉率变异性的标度指数。对短期、中期和长期区间的重复分析表明，只有在短期和中期区间才有明显的分数型指数。由于帕特是交感神经激活的替代者，我们的结果表明，在REM睡眠期间交感神经激活的变化具有类似于分数的行为。
Previous studies utilizing detrended fluctuation analysis (DFA) of heart rate variability during sleep revealed a higher fractal exponent during rapid eye movement (REM) sleep than non-REM sleep. The aim of this study was to determine whether the same difference exists in the variations of peripheral arterial tone (PAT). Finger pulse wave measured by a novel plethysmographic technique was monitored during sleep in 12 chronic heart failure patients, 8 heavy snorers, and 12 healthy volunteers. For each subject, at least two 15-min time series were constructed from the interpulse intervals and from pulse wave amplitudes during REM and non-REM sleep. Fractal scaling exponents of both types of time series were significantly higher for REM than non-REM sleep in all groups. In each of the groups and in both sleep stages, the fractal scaling exponents based on pulse wave amplitude were significantly higher than those based on pulse rate variability. A repeat of the analysis for short- ,intermediate-, and long-term intervals revealed that the fractallike exponents were evident only in the short- and intermediate- term intervals. Because PAT is a surrogate of sympathetic activation, our results indicate that variations in sympathetic activation during REM sleep have a fractallike behavior.