From Peers to Lay Bystanders: Findings from a Decade of Naloxone Distribution in Pittsburgh, PA
From Peers to Lay Bystanders: Findings from a Decade of Naloxone Distribution in Pittsburgh, PA
复制标题
DOI：
10.1080/02791072.2018.1430409
复制
发表时间：
2018-01-01
影响因子：
2.8
通讯作者：
Davis, Corey
中科院分区：
文献类型：
--
作者：
Bennett, Alex S.;Bell, Alice;Davis, Corey
阿片类药物过量逆转药物纳洛酮的分发一直是美国抗击阿片类药物流行病的核心。本报告提供了来自匹兹堡预防点 (PPP) 的数据，该组织是一个公共卫生倡导和直接服务组织，自 2005 年以来一直在实施过量预防计划 (OPP) 并分发纳洛酮。该计划最初仅向阿片类药物使用者 (PWUO) 提供纳洛酮培训和分发。 2015 年，州法律的修改使 PPP 能够向任何有能力应对阿片类药物过量用药的人提供纳洛酮。本报告考察了 2006 年 1 月 1 日至 2015 年 12 月 31 日期间通过 PPP 接受过量预防和纳洛酮管理培训的 1330 名 PWUO 的特征和纳洛酮相关经验，并比较了 PWUO 与 2015 年 1 月 1 日至 2015 年 12 月 31 日期间接受培训的 619 名非使用者的纳洛酮补充回报率。州法律变更后获得纳洛酮的人数， PWUO——尤其是海洛因使用者——更有可能逆转服药过量并返回 PPP 补充纳洛酮。根据这些发现，我们建议资源有限的社区组织优先向 PWUO 分发纳洛酮。
Distribution of the opioid overdose reversal drug naloxone has been central to efforts to combat the ongoing opioid epidemic in the United States. This report presents data from Prevention Point Pittsburgh (PPP), a public health advocacy and direct service organization that has operated an overdose prevention program (OPP) with naloxone distribution since 2005. The program initially provided naloxone training and distribution only to people who use opioids (PWUO). In 2015, a change to state law enabled PPP to provide naloxone to anyone in a position to respond to an opioid-related overdose. This report examines the characteristics and naloxone-related experiences of 1330 PWUO trained in overdose prevention and naloxone administration by PPP between January 1, 2006, and December 31, 2015, and compares rates of return for a naloxone refill by PWUO and the 619 non-users trained between January 1, 2015, and December 31, 2015. While larger numbers of individuals obtained naloxone after state law changed, PWUO-especially heroin users-were significantly more likely to reverse an overdose and return to PPP for a naloxone refill. Based on these findings, we recommend that resource-limited, community-based organizations prioritize the distribution of naloxone to PWUO.