Optical coherence tomography evaluation of macular edema after intravitreal triamcinolone acetonide in patients with parafoveal telangiectasis
Optical coherence tomography evaluation of macular edema after intravitreal triamcinolone acetonide in patients with parafoveal telangiectasis
复制标题
DOI：
10.1177/112067210601600508
复制
发表时间：
2006-09-01
影响因子：
1.7
通讯作者：
Perente, I.
中科院分区：
文献类型：
--
作者：
Cakir, M.;Kapran, Z.;Perente, I.
目的。中央凹旁毛细血管扩张（PT）是一种发育或获得的微血管异常的黄斑。异常的中央凹旁毛细血管渗漏导致黄斑水肿，随后导致视力下降。玻璃体内注射曲安奈德近年来被广泛应用于眼内增生性、水肿和新生血管疾病的治疗。本报告介绍了三例经玻璃体内注射曲安奈德（IVTA）的PT患者的评价。采用眼底荧光素血管造影（FA）和光学相干断层扫描（OCT）对患者进行随访。经睫状体平面静脉注射曲安奈德4 mg后，黄斑水肿血管造影改善，OCT视网膜厚度减小，视力和主观视力评分均有改善。本研究结果提示，玻璃体腔内注射曲安奈德可能是一种提高视力和减少FA血管渗漏的治疗选择。在IVTA手术后，对这些患者进行OCT和FA的随访对于正确的临床评估很重要。对这种方法的进一步研究似乎是有必要的。
PURPOSE. Parafoveal telangiectasis (PT) is a developmental or acquired microvascular abnormality of the macula. Leakage of the abnormal parafoveal capillaries leads to macular edema with subsequent decrease in visual acuity. Intravitreal triamcinolone acetonide is recently widely used in the management of intraocular proliferative, edematous, and neovascular diseases.METHODS. This report presents the evaluation of three cases with PT in whom intravitreal triamcinolone acetonide (IVTA) injection was performed. Fundus fluorescein angiography (FA) and optical coherence tomography (OCT) were used in follow-up of the patients.RESULTS. Following pars plana intravitreal injection of 4 mg of triamcinolone acetonide, the patients had angiographic improvement of the macular edema and minimal decrease in retinal thickness on OCT, accompanied by improvement in visual acuity and subjective visual assessment.CONCLUSIONS. The results of the present study on parafoveal capillary telangiectasis suggest that the intravitreal injection of triamcinolone acetonide may be a therapeutic option to increase visual acuity and decrease vascular leakage on FA. Following IVTA procedure, follow-up of these patients with both OCT and FA is important for correct clinical evaluation. Future studies on this method seem to be warranted.