Copper-Catalyzed Stereodefined Construction of Acrylic Acid Derivatives from Terminal Alkynes via CO2 Insertion
Copper-Catalyzed Stereodefined Construction of Acrylic Acid Derivatives from Terminal Alkynes via CO2 Insertion
复制标题
铜催化通过 CO2 插入从末端炔烃立体构建丙烯酸衍生物
DOI：
10.1021/acs.orglett.6b03860
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发表时间：
2017
期刊：
影响因子：
5.2
通讯作者：
M. Kimura
中科院分区：
文献类型：
--
作者：
K. Kuge;Y. Luo;Y. Fujita;Y. Mori;G. Onodera;M. Kimura
IPrCuCl催化炔基三烷基硼酸酯经1，2-烷基迁移生成的二烷基乙烯基硼烷中间体的CO2插入反应，合成了具有良好区域选择性和立体选择性的α-烷基丙烯酸。
IPrCuCl catalyzes the CO2insertion reaction undergone by a dialkylvinylborane intermediate derived from alkynyltrialkylborate by a 1,2-alkyl group migration to afford α-alkyl acrylic acids with excellent regio- and stereoselectivities.