Development and Psychometric Assessment of Novel Item Banks for Hereditary Retinal Diseases
Development and Psychometric Assessment of Novel Item Banks for Hereditary Retinal Diseases
复制标题
DOI：
10.1097/opx.0000000000001317
复制
发表时间：
2019-01-01
影响因子：
1.4
通讯作者：
Pesudovs, Konrad
中科院分区：
文献类型：
--
作者：
Senthil, Mallika Prem;Khadka, Jyoti;Pesudovs, Konrad
重要性：本研究开发了遗传性视网膜疾病患者10个生活质量（QoL）领域的心理测量学有效项目库，这将使临床医生和研究人员能够探索遗传性视网膜疾病对QoL各个方面的影响。目的：本研究的目的是使用Rasch分析评估遗传性视网膜疾病QoL项目库的心理测量学特性，并证明计算机化自适应测试（CAT）系统在获得精确的测量QoLusing只有少数items.METHODS：遗传性视网膜疾病项目银行回答了233名参与者（中位年龄，58岁;范围，18至94岁;女性参与者，59%）。遗传性视网膜疾病项目库涵盖10个QoL领域：活动受限、移动性、情感、社交、便利、经济、健康问题、视觉症状、眼部舒适症状和一般症状。Rasch分析评估了10个项目银行的心理测量学特性，并提供项目校准的发展CAT。计算机自适应测试模拟进行计算所需的项目，以获得精确测量每个QoL domain.RESULTS：方便，经济，视觉症状，和社会领域形成一维尺度的平均数。然而，活动限制和健康问题领域表现出多维性，需要进行重大修改来解决这一问题，这导致了四个新的QoL领域，即阅读、驾驶、照明和对疾病进展的关注。共10个项目库进行CAT模拟测试，这表明，需要8至12个项目，以获得每个QoL领域的精确测量。结论：我们已经开发了10个心理测量学有效的项目库tomesure与遗传性视网膜疾病的人相关的QoL领域。平均而言，仅需5个和10个项目即可获得中等和高精度测量。
SIGNIFICANCE: This study develops psychometrically valid itembanks across 10 areas of quality of life (QoL) specific to people with hereditary retinal diseases, which will enable clinicians and researchers to explore the impact of hereditary retinal diseases across all aspects of QoL.PURPOSE: The purpose of this study was to assess the psychometric properties of hereditary retinal disease QoL item banks using Rasch analysis and demonstrate the effectiveness of a computerized adaptive testing (CAT) system in obtaining precise measurement of QoL using only a few items.METHODS: The hereditary retinal disease item banks were answered by 233 participants (median age, 58 years; range, 18 to 94 years; female participants, 59%). The hereditary retinal disease itembanks cover 10 QoL domains: activity limitation, mobility, emotional, social, convenience, economic, health concerns, visual symptoms, ocular comfort symptoms, and general symptoms. Rasch analysis assessed the psychometric properties of the 10 item banks and provided item calibrations for the development of CAT. Computerized adaptive testing simulations were performed to calculate the average number of items required to gain precise measurement of each QoL domain.RESULTS: The convenience, economic, visual symptoms, and the social domains formed unidimensional scales. However, the activity limitation and health concerns domains demonstrated multidimensionality and requiredmajor modifications to resolve this, which resulted in four new QoL domains, namely, reading, driving, lighting, and concerns about the disease progression. In total, 10 item banks underwent CAT simulation testing, which indicated that 8 to 12 items were required to gain precise measurement of each QoL domain.CONCLUSIONS: We have developed 10 psychometrically valid item banks tomeasure the QoL domains relevant to people with hereditary retinal diseases. On average, only 5 and 10 items were required to gainmeasurement atmoderate and high precision, respectively.