Mother's own milk dose is associated with decreased time from initiation of feedings to discharge and length of stay in infants with gastroschisis
Mother's own milk dose is associated with decreased time from initiation of feedings to discharge and length of stay in infants with gastroschisis
复制标题
DOI：
10.1038/s41372-020-0595-3
复制
发表时间：
2020-01-28
影响因子：
2.9
通讯作者：
Patel, Aloka L.
中科院分区：
文献类型：
--
作者：
Storm, Andrew P.;Bowker, Rakhee M.;Patel, Aloka L.
目的探讨腹裂修补术后母乳摄入量与开始喂养至出院时间的关系。次要结局包括肠外营养（PN）持续时间和住院时间（LOS）。研究设计：回顾性研究44例腹裂婴儿的人口统计学资料、腹裂类型、PN天数、营养里程碑的时间、喂养成分和LOS。结果：剂量增加10%与从进食开始到出院的时间缩短显著相关（剂量增加10%，出院的校正风险比[HR]为1.111; 95%CI为1.011-1.220，p = 0.029）。顺铂剂量也与较短的LOS显著相关（顺铂剂量每增加10%，出院时校正的HR为1.130; 95% CI，1.028-1.242，p = 0.011）。结论：剂量依赖性地降低了从进食开始到出院的时间和LOS。腹裂患者的母亲应接受教育和积极的哺乳支持，以优化喂养的婴儿量。
Objective To determine if mother's own milk (MOM) dose after gastroschisis repair is associated with time from feeding initiation to discharge. Secondary outcomes included parenteral nutrition (PN) duration and length of stay (LOS). Study design Retrospective study of 44 infants with gastroschisis examined demographics, gastroschisis type, PN days, timing of nutrition milestones, feeding composition, and LOS. Results MOM dose was significantly associated with shorter time to discharge from feeding initiation (adjusted hazard ratio [HR] for discharge per 10% increase in MOM dose, 1.111; 95% CI, 1.011-1.220, p = 0.029). MOM dose was also significantly associated with shorter LOS (adjusted HR for discharge per 10% increase in MOM dose, 1.130; 95% CI, 1.028-1.242, p = 0.011). Conclusions MOM dose was significantly associated with a decrease in time to discharge from feeding initiation and LOS in a dose-dependent manner. Mothers of gastroschisis patients should receive education and proactive lactation support to optimize MOM volume for feedings.