Splenic and superior mesenteric artery thrombolytic infusion therapy for acute portal and mesenteric vein thrombosis.

Splenic and superior mesenteric artery thrombolytic infusion therapy for acute portal and mesenteric vein thrombosis.
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脾和肠系膜上动脉溶栓输注治疗急性门静脉和肠系膜静脉血栓。

DOI:
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发表时间:
2007
期刊:
Canadian journal of surgery. Journal canadien de chirurgie
影响因子:
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通讯作者:
V. Prabhudesai
V. Prabhudesai
中科院分区:
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文献类型:
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作者:
N. Safieddine;J. Mamazza;A. Common;V. Prabhudesai

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肠缺血是一种与高发病率和死亡率相关的疾病。肠系膜静脉血栓形成是一种罕见的肠缺血原因,约占此类病例的5%-15%门静脉/肠系膜上静脉血栓形成导致肠缺血的手术干预充满了困难,因为需要切除肠的程度和无法解决潜在的血栓形成。我们报告一例急性肠缺血继发于门静脉和肠系膜上静脉(SMV)血栓形成成功治疗组织纤溶酶原激活剂(tPA)经肠系膜上动脉(SMA)和脾动脉(一个以前未用于此目的的途径)。
Intestinal ischemia is a condition associated with a high degree of morbidity and mortality. Mesenteric venous thrombosis is an uncommon cause of intestinal ischemia accounting for 5%–15% of such cases.1 Surgical intervention in cases of intestinal ischemia resulting from portal/superior mesenteric vein thrombosis is fraught with difficulty owing to the extent of bowel resection required and the inability to address the underlying thrombosis. We present a case report of acute intestinal ischemia secondary to portal and superior mesenteric vein (SMV) thrombosis successfully treated with tissue plasminogen activator (tPA) via the superior mesenteric artery (SMA) and splenic artery (a route not previously used for this purpose).