CT colonography: does improved z resolution help computer-aided polyp detection?

CT colonography: does improved z resolution help computer-aided polyp detection?
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CT 结肠成像:提高 z 分辨率是否有助于计算机辅助息肉检测?

DOI:
10.1118/1.1599985
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发表时间:
2003
期刊:
影响因子:
3.8
通讯作者:
Napel,Sandy
Napel,Sandy
中科院分区:
医学3区
文献类型:
--
作者:
Sundaram,Padmavathi;Beaulieu,ChristopherF;Paik,DavidS;Schraedley-Desmond,Pamela;Napel,Sandy

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多层螺旋CT在给定的探测器准直设置下提供了几种纵向(z)分辨率的回顾性选择。我们试图确定z分辨率对计算机辅助结肠息肉检测器性能的影响,因为人类读取器和计算机辅助息肉检测器在不同的z分辨率下可能具有最佳性能。我们在体模数据集以及从单个患者获得的数据上运行计算机辅助息肉检测算法。所有数据均在1.25至10 mm的不同切片厚度下进行重建。我们使用自由响应接收器操作特性分析研究了探测器在各种息肉尺寸范围内的性能。我们还研究了对比噪声比(CNR)作为切片厚度和息肉大小的函数。对于体模数据,将切片厚度从5 mm降低到1.25 mm将灵敏度从84.5%提高到98.3%(所有息肉),从61.4%提高到95.5%(范围[0,5] mm内的息肉),从97.7%提高到100%(范围[5,10] mm内的息肉),每个数据集的假阳性率为20。对于大于10 mm的息肉,当切片厚度减小时,检测灵敏度没有显著提高。CNR随切片厚度和息肉大小表现出预期的行为,但在所有病例中均保持较高(> 4)。患者数据的结果遵循与体模病例相似的模式。因此,我们得出结论,对于这种检测器,最佳切片厚度取决于要检测的最小息肉的大小。对于10 mm及更大息肉的检测,5 mm切片的重建可能就足够了。需要进一步的研究来将这些结果推广到更广泛的患者人群中,这些患者在不同的扫描仪上扫描。
Multislice helical CT offers several retrospective choices of longitudinal (z) resolution at a given detector collimation setting. We sought to determine the effect ofzresolution on the performance of a computer‐aided colonic polyp detector, since a human reader and a computer‐aided polyp detector may have optimal performances at differentzresolutions. We ran a computer‐aided polyp detection algorithm on phantom data sets as well as data obtained from a single patient. All data were reconstructed at various slice thicknesses ranging from 1.25 to 10 mm. We studied the performance of the detector at various ranges of polyp sizes using free‐response receiver‐operating characteristic analyses. We also studied contrast‐to‐noise ratios (CNR) as a function of slice thickness and polyp size. For the phantom data, reducing the slice thickness from 5 to 1.25 mm improves sensitivity from 84.5% to 98.3% (all polyps), from 61.4% to 95.5% (polyps in the range [0, 5) mm) and from 97.7% to 100% (polyps in the range [5, 10) mm) at a false positive rate of 20 per data set. For polyps larger than 10 mm, there is no significant improvement in detection sensitivity when slice thickness is reduced. CNRs showed expected behavior with slice thickness and polyp size, but in all cases remained high (> 4). The results for the patient data followed similar patterns to that of the phantom case. Thus we conclude that for this detector, the optimal slice thickness is dependent upon the size of the smallest polyps to be detected. For detection of polyps 10 mm and larger, reconstruction of 5 mm sections may be sufficient. Further study is required to generalize these results to a broader population of patients scanned on different scanners.
DOI: 10.1148/radiology.216.1.r00jl43284
发表时间: 2000-07-01
期刊: RADIOLOGY
影响因子: 19.7
作者:
Summers, RM;Beaulieu, CF;Napel, S
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DOI: --
发表时间: 2002
影响因子: 1.3
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DOI: --
发表时间: 2002
期刊: Abdominal Imaging
影响因子: --
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DOI: 10.1118/1.596464
发表时间: 1990-11-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
CRAWFORD, CR;KING, KF
通讯作者: KING, KF
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DOI: --
发表时间: 2001
期刊: International Conference on Medical Image Computing and Computer-Assisted Intervention
影响因子: --
作者:
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