IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes
IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes
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DOI：
10.1093/nar/gki010
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Lefranc, MP
中科院分区：
文献类型：
--
作者：
Giudicelli, W;Chaume, D;Lefranc, MP
IMGT/Gene-DB是来自人和小鼠的免疫球蛋白（IG）和T细胞受体（TR）基因的综合IMGT基因组数据库，以及来自其他脊椎动物的发育。 IMGT/Gene-DB是IG和TR基因命名法的国际参考，并与Hugo命名委员会，小鼠基因组数据库和其他物种的基因组委员会密切合作。 IMGT/Gene-DB允许通过基因座，组和亚组对IG和TR基因进行搜索，这是IMGT-主页的分类概念。捷径可以通过基因名称或克隆名称检索基因信息。与可配置的URL的直接链接可访问人类或程序可用的信息。 IMGT/Gene-DB条目显示与基因组（基因定位），等位基因多态性（等位基因的数量，IMGT参考序列，功能等）基因表达（已知cDNA），蛋白质和结构（蛋白质显示，IMGT，IMGT，IMGT Colliers de Perles）。它提供了指向IMGT序列数据库以及IMGT曲目Web资源的内部链接，以及指向基因组和通才序列数据库的外部链接。 IMGT/Gene-DB管理IMGT工具用于IG和TR基因和等位基因比较和分配的IMGT参考目录，以及用于基因数据注释的IMGT数据库。 imgt/gene-db可以在http://imgt.cines.fr上免费获得。
IMGT/GENE-DB is the comprehensive IMGT genome database for immunoglobulin (IG) and T cell receptor (TR) genes from human and mouse, and, in development, from other vertebrates. IMGT/GENE-DB is the international reference for the IG and TR gene nomenclature and works in close collaboration with the HUGO Nomenclature Committee, Mouse Genome Database and genome committees for other species. IMGT/GENE-DB allows a search of IG and TR genes by locus, group and subgroup, which are CLASSIFICATION concepts of IMGT-ONTOLOGY. Short cuts allow the retrieval gene information by gene name or clone name. Direct links with configurable URL give access to information usable by humans or programs. An IMGT/GENE-DB entry displays accurate gene data related to genome (gene localization), allelic polymorphisms (number of alleles, IMGT reference sequences, functionality, etc.) gene expression (known cDNAs), proteins and structures (Protein displays, IMGT Colliers de Perles). It provides internal links to the IMGT sequence databases and to the IMGT Repertoire Web resources, and external links to genome and generalist sequence databases. IMGT/GENE-DB manages the IMGT reference directory used by the IMGT tools for IG and TR gene and allele comparison and assignment, and by the IMGT databases for gene data annotation. IMGT/ GENE-DB is freely available at http://imgt.cines.fr.