Dermoscopy of desmoplastic melanoma: report of six cases
Dermoscopy of desmoplastic melanoma: report of six cases
复制标题
DOI：
10.1111/j.1365-2133.2008.08687.x
复制
发表时间：
2008-08-01
影响因子：
10.3
通讯作者：
Thomas, L.
中科院分区：
文献类型：
--
作者：
Debarbieux, S.;Ronger-Salve, S.;Thomas, L.
背景 促纤维增生性黑色素瘤（DM）是皮肤黑色素瘤的一种罕见变体。其不寻常的临床表现常常导致诊断延迟。DM的皮肤镜特征尚未被描述。
目的 明确DM的皮肤镜特征。
患者和方法 一项基于单一机构登记的回顾性研究，涉及6例经组织学证实且有皮肤镜数据的促纤维增生性黑色素瘤病例。我们研究的标准包括：网状结构、色素点和小球、条纹、消退特征、溃疡、颜色数量、蓝白幕以及血管模式。
结果 只有3例表现出黑素细胞病变的一种典型特征；其他病例是基于存在消退表现（全部6例），即白色瘢痕样区域和“胡椒粉样”改变（6例中的3例）、多种（>4种）颜色（6例中的5例）以及与黑色素瘤相关的血管模式（5例），如线状不规则血管（4例）和乳红色区域（2例）而被识别。
讨论 我们认为皮肤镜有助于准确诊断这种罕见的肿瘤。在缺乏色素网的情况下，应注意识别消退特征以及与黑色素瘤相关的血管模式。
Background Desmoplastic melanoma (DM) is a rare variant of cutaneous melanoma. Its diagnosis is often delayed by an unusual clinical presentation. The dermoscopic features of DM have not yet been described.Objective To define the dermoscopic features of DM.Patients and methods A single-institution register-based retrospective study of six cases of histology-proven desmoplastic melanoma for which dermoscopy data were available. The criteria we studied included: network, dots and globules, streaks, regression features, ulceration, number of colours, blue/white veil, and vascular pattern.Results Only three cases exhibited one classical feature for a melanocytic lesion; other cases were recognized on the basis of the presence of figures of regression (all six), i.e. white scar-like areas and 'peppering' (three of six), multiple (> 4) colours (five of six), and of melanoma-related vascular patterns (five) such as linear-irregular vessels (four) and milky-red areas (two).Discussion We believe that dermoscopy could help in the accurate diagnosis of this rare neoplasm. In the absence of a pigmented network, attention should be given to the identification of features of regression and to melanoma-associated vascular patterns.