Effects of intralaminar thalamic stimulation on language functions

Effects of intralaminar thalamic stimulation on language functions
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DOI:
10.1016/j.bandl.2004.05.002
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发表时间:
2005-01-01
期刊:
影响因子:
2.5
通讯作者:
Mandybur, GT
Mandybur, GT
中科院分区:
心理学3区
文献类型:
--
作者:
Bhatnagar, SC;Mandybur, GT

文献摘要

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15名正在接受丘脑慢性电极植入治疗运动障碍和慢性疼痛的神经外科受试者,接受了一系列神经语言功能的评估,以确定刺激丘脑中央内侧核是否影响语言和认知加工。对数据的分析表明,刺激左侧中央内侧核对语言功能的处理产生了显著的易化影响;这种易化效应是通过产生错误的数量和患者的反应潜伏期来衡量的。还注意到,便利作用已扩展到其他语文职能。本文讨论了刺激左侧中央内侧核(脑干网状结构的延伸)对语言功能易化的本质。(C)2004 Elsevier Inc.保留所有权利。
Fifteen neurosurgical subjects, who were undergoing thalamic chronic electrode implants as a treatment for dyskinesia and chronic pain, were evaluated on a series of neurolinguistic functions to determine if the stimulation of the centromedianum nucleus of the thalamus affected language and cognitive processing. Analysis of the data revealed that the stimulation of the left centro-medianurn nucleus had resulted in a notable facilitatory influence on the processing of language functions; this facilitatory effect was measured in terms,of the number of errors produced and the patients' response latency time. The facilitatory effect was also noted to have extended to other language functions. The nature of the facilitation from the stimulation of the left centromedianum nucleus, an extension of the brainstem reticular formation, on language functions is discussed. (C) 2004 Elsevier Inc. All rights reserved.