Gm Allotyping to Determine the Origin of the Anti‐D Causing Hemolytic Anemia in a Kidney Transplant Recipient
Gm Allotyping to Determine the Origin of the Anti‐D Causing Hemolytic Anemia in a Kidney Transplant Recipient
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转基因同种异型确定肾移植受者中导致溶血性贫血的抗 D 来源
DOI：
10.1111/j.1423-0410.1987.tb03033.x
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发表时间：
1987
期刊：
影响因子：
2.7
通讯作者：
M. Chopek
中科院分区：
文献类型：
--
作者：
J. Swanson;E. Sebring;Robert Sastamoinen;M. Chopek
抽象的。在一名接受D阴性母亲肾移植的D阳性患者的血清和红细胞中发现了导致轻度溶血性贫血的抗D抗体。移植前在供体血清中检测到抗D抗体。对患者血清、供体血清、供体抗D和移植后血清中未预期的抗D进行了GM同种异型分型，结果显示抗体为母体来源。患者为Gm（fb），供体为Gm（agfb），母体为抗D Gm（afb），移植后血清中的抗D为Gm（a）。
Abstract. Anti‐D causing mild hemolytic anemia was found in the serum and on the red cells of a D‐positive patient who had received a kidney transplant from his D‐negative mother. Anti‐D had been detected in the donor's serum before transplantation. Gm allotyping of the patient's serum, donor's serum, donor's anti‐D, and the unex pected anti‐D in the posttransplantation serum showed the antibody to be of maternal origin. The patient was Gm(fb), the donor Gm(agfb), the maternal anti‐D Gm (afb), and the anti‐D in the posttransplantation serum was Gm(a).