Electric field generated by axial longitudinal vibration modes of microtubule
Electric field generated by axial longitudinal vibration modes of microtubule
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DOI：
10.1016/j.biosystems.2010.02.007
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发表时间：
2010-05-01
期刊：
影响因子：
1.6
通讯作者：
Kucera, O.
中科院分区：
文献类型：
--
作者：
Cifra, M.;Pokorny, J.;Kucera, O.
微管是满足在kHz至GHz区域中产生振荡电场的先决条件的电极结构。用于激发微管中的弹性电振动的能量供应可以由GTP水解、马达蛋白-微管相互作用和来自线粒体的能量流出提供。本文计算了微管轴向纵向振动模在随机激发和相干激发下产生的电场。在振动相干激发的情况下，电场强度在微管末端最高。电场对周围分子施加的介电泳力将通过改变电荷和质量粒子的传输概率来影响微管聚合的动力学。由电极细胞结构振动产生的电场有望在生物自组织中发挥重要作用。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Microtubules are electrically polar structures fulfilling prerequisites for generation of oscillatory electric field in the kHz to GHz region. Energy supply for excitation of elasto-electrical vibrations in microtubules may be provided from GTP-hydrolysis; motor protein-microtubule interactions; and energy efflux from mitochondria. We calculated electric field generated by axial longitudinal vibration modes of microtubules for random, and coherent excitation. In case of coherent excitation of vibrations, the electric field intensity is highest at the end of microtubule. The dielectrophoretic force exerted by electric field on the surrounding molecules will influence the kinetics of microtubule polymerization via change in the probability of the transport of charge and mass particles. The electric field generated by vibrations of electrically polar cellular structures is expected to play an important role in biological self-organization. (C) 2010 Elsevier Ireland Ltd. All rights reserved.