Developmental biomechanics of the cervical spine: Tension and compression.
Developmental biomechanics of the cervical spine: Tension and compression.
复制标题
颈椎的发育生物力学：张力和压力。
DOI：
10.1016/j.jbiomech.2005.10.014
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发表时间：
2006
影响因子：
2.4
通讯作者：
R. Ching
中科院分区：
文献类型：
--
作者：
D. Nuckley;R. Ching
流行病学数据和临床指标揭示了与儿童颈部损伤相关的毁灭性后果。不幸的是，如果不了解颈椎发育生物力学，无论是损伤预防还是临床管理策略都不能有效地减少这些损伤或其对儿童的影响。因此，我们在狒狒模型中研究了脊柱发育与颈椎功能（刚度）和失效生物力学特征之间的关系。一项相关研究设计被用来定义脊髓组织成熟和脊柱生物力学在张力和压缩之间的关系。18只狒狒的颈椎标本分布在发育谱上（相当于人类1-26岁），被解剖成骨少的功能脊柱单元。采用伺服液压MTS，对c - c2、C3-C4、C5-C6、C7-T1试件进行了非破坏性的拉伸和压缩试验，并在测量六轴载荷和位移的同时进行了拉伸破坏。描述颈椎刚度和归一化刚度的发育生物力学反应的功能在张力和压缩载荷中都表现出显著的直接关系。同样，拉伸破坏载荷和归一化破坏载荷表现出显著的成熟增长。此外，在检查的脊柱水平之间观察到生物力学反应的差异，所有水平都表现出临床相关的失败模式。这些数据支持了我们从发育生物力学角度对儿童颈椎的理解，并促进了损伤预防或管理方案的发展，以减轻儿童脊柱损伤及其有害影响。
Epidemiological data and clinical indicia reveal devastating consequences associated with pediatric neck injuries. Unfortunately, neither injury prevention nor clinical management strategies will be able to effectively reduce these injuries or their effects on children, without an understanding of the cervical spine developmental biomechanics. Thus, we investigated the relationship between spinal development and the functional (stiffness) and failure biomechanical characteristics of the cervical spine in a baboon model. A correlation study design was used to define the relationships between spinal tissue maturation and spinal biomechanics in both tension and compression. Eighteen baboon cervical spine specimens distributed across the developmental spectrum (1–26 human equivalent years) were dissected into osteoligamentous functional spinal units. Using a servo-hydraulic MTS, these specimens (Oc–C2, C3–C4, C5–C6, C7–T1) were non-destructively tested in tension and compression and then displaced to failure in tension while measuring the six-axes of loads and displacements. The functions describing the developmental biomechanical response of the cervical spine for stiffness and normalized stiffness exhibited a significant direct relationship in both tension and compression loading. Similarly, the tensile failure load and normalized failure load demonstrated significant maturational increases. Further, differences in biomechanical response were observed between the spinal levels examined and all levels exhibited clinically relevant failure patterns. These data support our understanding of the child cervical spine from a developmental biomechanics perspective and facilitate the development of injury prevention or management schema for the mitigation of child spine injuries and their deleterious effects.