Chronic Shedders as Reservoir for Nosocomial Transmission of Norovirus

Chronic Shedders as Reservoir for Nosocomial Transmission of Norovirus
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DOI:
10.1128/jcm.01308-10
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发表时间:
2010-11-01
影响因子:
9.4
通讯作者:
Koopmans, Marion
Koopmans, Marion
中科院分区:
医学2区
文献类型:
--
作者:
Sukhrie, Faizel H. A.;Siebenga, J. Joukje;Koopmans, Marion

文献摘要

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免疫功能低下患者的诺如病毒(NoV)感染可能会导致诺如病毒长时间脱落。在这里,我们展示了三名慢性排毒者与医院暴发的关系。流行病学和分子证据相结合表明,在一个病例中,NoV 传播发生在首次诊断后至少 17 天。
Norovirus (NoV) infection in immunocompromised patients may lead to prolonged norovirus shedding. Here, we demonstrate the involvement of three chronic shedders in hospital outbreaks. Combined epidemiological and molecular evidence suggests that in one case, NoV transmission occurred at least 17 days after the first diagnosis.