Unitary study on evoked activity of callosal neurons and its effect on pyramidal tract cell activity on cats.
Unitary study on evoked activity of callosal neurons and its effect on pyramidal tract cell activity on cats.
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猫胼胝体神经元诱发活动及其对锥体束细胞活性影响的单一研究。
DOI：
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发表时间：
1959
期刊：
影响因子：
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通讯作者：
K. Okamoto
中科院分区：
文献类型：
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作者：
H. Asanuma;K. Okamoto
对猫的两种皮层细胞进行了微电极实验，每种细胞都通过逆向刺激进行识别。首先，从胼胝体神经元中进行记录，并通过桡神经刺激来研究这些记录。其次，对锥体束细胞（P.T.细胞）进行记录，研究胼胝体刺激对P.T.细胞活性的影响。所有研究均在周十字皮层中进行。获得以下结果：1)在被鉴定为胼胝体神经元的20个细胞中，有12个是由传递到浅层桡神经的单一刺激激发的。放电潜伏期为12至20毫秒。2)对胼胝体的单次刺激对P.T.细胞产生持久的抑制作用。抑制作用似乎在 20 至 30 毫秒的潜伏期开始。虽然对于大多数细胞来说，这种效应纯粹是抑制性的（表 1），但在极少数情况下，抑制前会出现短暂的兴奋。3) 在 P.T. 细胞的一些成功的细胞内记录中，观察到当放电受到抑制时，会发生明显的膜超极化。
Microelectrode experiments were made on two kinds of cortical cells in the cat, each identified by antidromic stimulation. First, recordings were made from callosal neurons, and these were studied by radial nerve stimulation. Second, recordings were made from pyramidal tract cells (P. T. cells), and the effects of corpus callosum stimulation on the activities of P. T. cells were studied. All studies were carried out in the pericruciate cortex. The following results were obtained;1) Out of 20 cells identified as callosal neurons, 12 were fired by single stimuli delivered to the superficial radial nerve. The latency of the discharge ranged from 12 to 20msec.2) Single stimuli to the corpus callosum produced long lasting inhibitory effects on P. T. cells. The inhibitory effect seemed to start with a latency of 20 to 30msec. Though with most cells the effect was purely inhibitory (table 1), on rare occasions a transitory excitation preceded the inhibition.3) In a few successful intracellular recordings from P. T. cells, a marked hyperpolarization of the membrane was observed to occur when firing was inhibited.