Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skin
Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skin
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局部用吡美莫司和他克莫司可短暂诱导小鼠皮肤中的神经肽释放和肥大细胞脱粒
DOI：
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发表时间：
2007
影响因子：
10.3
通讯作者：
M. Steinhoff
中科院分区：
文献类型：
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作者：
S. Ständer;H. Ständer;S. Seeliger;T. Luger;M. Steinhoff
背景局部钙调磷酸酶抑制剂吡美莫司和他克莫司已被证明是一种有效的新型抗炎疗法。唯一与临床相关的副作用报道是局部治疗开始时短暂的应用部位灼烧和刺痛瘙痒。
Background The topical calcineurin inhibitors pimecrolimus and tacrolimus have been demonstrated to be an effective new anti‐inflammatory therapy. The only clinically relevant side‐effect reported is transient application site burning and stinging itch at the beginning of topical therapy.