Validation of the Generalized Anxiety Disorder-7 (GAD-7) among Chinese people with epilepsy
Validation of the Generalized Anxiety Disorder-7 (GAD-7) among Chinese people with epilepsy
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DOI：
10.1016/j.eplepsyres.2015.11.019
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发表时间：
2016-02-01
影响因子：
2.2
通讯作者：
Zhou, Dong
中科院分区：
文献类型：
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作者：
Tong, Xin;An, Dongmei;Zhou, Dong
目的：在中国癫痫患者（PWE）中验证中文版广泛性焦虑症-7（GAD-7）。方法：招募来自华西医院的连续队列PWE。每个患者都接受了精神病学评估，包括小型国际神经精神病学访谈 (MINI) 和 GAD-7。收集人口统计学和临床特征。计算Cronbach's a系数并进行受试者工作曲线（ROC）分析。结果：共有213名PWE完成了精神病学评估。 GAD-7 很容易理解，所有参与者都能快速完成。根据 MINI 标准，50 名患者 (23.5%) 患有 GAD。 GAD-7 的 Cronbach 系数为 0.888。 ROC 分析显示曲线下面积为 0.974 (95% CI= 0.956-0.993)。在截止分数 >6 时，GAD-7 的最大约登指数为 0.854，敏感性为 94%，特异性为 91.4%，阳性预测值为 77%，阴性预测值为 98%。 意义：GAD-7 的中文版是中国 PWE 中筛查 GAD 的宝贵工具。 (C) 2015 Elsevier B.V. 保留所有权利。
Objective: To validate the Chinese version of the Generalized Anxiety Disorder-7 (GAD-7) in Chinese people with epilepsy (PWE).Methods: A consecutive cohort of PWE from the West China Hospital was recruited. Each patient received a psychiatric evaluation comprising the Mini International Neuropsychiatric Interview (MINI) and the GAD-7. Demographic and clinical characteristics were collected. Cronbach's a coefficient was calculated and receiver operating curve (ROC) analysis was conducted.Results: A total of 213 PWE completed the psychiatric evaluation. The GAD-7 was easily understood and quickly completed by all participants. Fifty patients (23.5%) had GAD according to the MINI criteria. Cronbach's a coefficient for the GAD-7 was 0.888. ROC analysis showed an area under the curve of 0.974 (95% CI= 0.956-0.993). At a cut-off score of >6, the GAD-7 achieved the largest Youden index of 0.854 with a sensitivity of 94%, a specificity of 91.4%, a positive predictive value of 77% and a negative predictive value of 98%.Significance: The Chinese version of the GAD-7 is a valuable tool for screening for GAD in Chinese PWE. (C) 2015 Elsevier B.V. All rights reserved.