Overexpression of septin-7 inhibits melatonin-induced cell apoptosis in human fetal osteoblastic cells via suppression of endoplasmic reticulum stress.

Overexpression of septin-7 inhibits melatonin-induced cell apoptosis in human fetal osteoblastic cells via suppression of endoplasmic reticulum stress.
复制标题

septin-7 的过度表达通过抑制内质网应激来抑制褪黑素诱导的人胎儿成骨细胞细胞凋亡。

DOI:
10.3892/mmr.2018.8449
复制
发表时间:
2018-03
影响因子:
3.4
通讯作者:
Qiu Shui
Qiu Shui
中科院分区:
医学4区
文献类型:
--
作者:
Meng XiaoTong;Zhu Yue;Tao Lin;Zhao SiChao;Qiu Shui

文献摘要

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我们以前的研究表明褪黑素可以通过诱导内质网应激(ERS)诱导人胎儿成骨细胞(hFOB)1.19细胞凋亡,最近的研究表明septin-7(SEPT 7)的表达,
Our previous study demonstrated that melatonin could induce apoptosis in the human fetal osteoblastic (hFOB) 1.19 cell line via induction of endoplasmic reticulum stress (ERS), and recent studies have demonstrated that the expression of septin‑7 (SEPT7) e