Incidence of autoimmune subepidermal blistering dermatoses in a region of central Germany.

Incidence of autoimmune subepidermal blistering dermatoses in a region of central Germany.
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德国中部地区自身免疫性表皮下起泡性皮肤病的发病率。

DOI:
10.1001/archderm.1995.01690200097021
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发表时间:
1995
影响因子:
--
通讯作者:
E. Bröcker
E. Bröcker
中科院分区:
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文献类型:
--
作者:
D. Zillikens;S. Wever;A. Roth;B. Weidenthaler‐Barth;T. Hashimoto;E. Bröcker

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我们怀着极大的兴趣阅读了Bernard等人1995年1月在《档案》上发表的关于表皮下自身免疫性大疱性皮肤病在法国三个地区的发病率和分布的文章。关于这些疾病的流行病学数据非常罕见,我们在维尔茨堡大学(德国)皮肤科进行了一项类似的研究。该中心是巴伐利亚西北部唯一的皮肤科,巴伐利亚是德国中部的一个地区。观察期为65个月(1989年3月至1994年7月),纳入本次调查的病例来自一个覆盖1.7× 106人口的地区。本研究中的所有患者均患有累及皮肤和/或粘膜的新获得性大疱性疾病。这些患者在我们的门诊就诊,大多数患者入院开始治疗。诊断标准见表1。所有患者
With great interest, we read the recent article by Bernard et al1in the January 1995 issue of theArchiveson the incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions. Epidemiologic data on these conditions had been extremely rare, and we undertook a similar study in the Department of Dermatology at the University of Wurzburg (Germany). This center is the only dermatologic department in northwestern Bavaria, a region of central Germany. The observation period was 65 months (March 1989 through July 1994), and cases included in this investigation came from an area covering a population of 1.7× 106. All patients in this study suffered from a newly acquired bullous disease involving the skin and/or the mucous membranes. These patients were seen in our outpatient clinic, and most were admitted for initiation of treatment. The diagnostic criteria are shown inTable 1. All patients