A computer-controlled aortic and mitral valve occluder.
A computer-controlled aortic and mitral valve occluder.
复制标题
计算机控制的主动脉和二尖瓣封堵器。
DOI：
10.1007/bf02738548
复制
发表时间：
1997
影响因子：
3.8
通讯作者：
Yellin,EL
中科院分区：
文献类型：
--
作者：
Solomon,SB;Nikolic,SD;Frater,RW;Yellin,EL
为了研究心脏力学，重要的是研究心脏搏动的变化。左心室舒张充盈特性由同时发生的心室舒张的被动成分和主动成分决定。为了分离心室充盈的主动和被动成分，我们设计了一个计算机控制的二尖瓣封堵器，以防止左心室充盈。设计了一种计算机控制的主动脉封堵器，以改变可能影响心室充盈成分的后负荷条件。在6只狗身上进行的实验表明，这些装置可以有效地控制心室内血流和射血。与之前报道的技术相比，计算机控制的主动脉和二尖瓣闭塞器具有更准确的触发和闭塞定时系统。这种计算机控制的设备使我们能够将被动成分，即填充成分与主动成分，心室松弛，分离开来，并同时改变后负荷，这将使我们能够更好地理解心室填充和射血是如何在搏动的基础上控制的。
To study cardiac mechanics, it is important to study the beat-to-beat changes in the heart. Left ventricular diastolic filling properties are determined by a passive component and an active component due to ventricular relaxation that occur simultaneously. To separate the active and passive components of ventricular filling, we designed a computer-controlled mitral valve occluder that prevents left ventricular filling. A computer-controlled aortic occluder was designed to change afterload conditions that could affect the components of ventricular filling. Experiments in six dogs demonstrated that these devices effectively control ventricular inflow and ejection on a beat-to-beat basis. The computer-controlled aortic and mitral occluders have a more accurate triggering and occlusion timing system than the previously, reported techniques. This computer-controlled device enabled us to separate the passive component, of filling from the active component, ventricular relaxation, and to alter afterload simultaneously, which will allow us to develop a better under-standing of how ventricular filling and ejection is controlled on a beat-to-beat basis.