STRENGTH CONDITIONING IN OLDER MEN - SKELETAL-MUSCLE HYPERTROPHY AND IMPROVED FUNCTION
STRENGTH CONDITIONING IN OLDER MEN - SKELETAL-MUSCLE HYPERTROPHY AND IMPROVED FUNCTION
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DOI：
10.1152/jappl.1988.64.3.1038
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发表时间：
1988-03-01
影响因子：
3.3
通讯作者：
EVANS, WJ
中科院分区：
文献类型：
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作者：
FRONTERA, WR;MEREDITH, CN;EVANS, WJ
在老年男性中确定了力量调节对骨骼肌功能和质量的影响。12名健康的未受过训练的志愿者（年龄在60-72岁之间）参加了为期12周的力量训练计划（8次重复/组；3组/天；3天/周），对双膝关节的伸肌和屈肌进行了一次最大重复量（1 RM）的80%。他们在项目开始前、培训6周和12周后接受了评估。每周1 RM的测量显示伸肌和屈肌的力量逐渐增加。到12周时，伸肌和屈肌强度分别增加了107.4 （P < 0.0001）和226.7% （P < 0.0001）。Cybex II型测功仪测得的伸肌和屈肌等速峰值扭矩在60度/秒时分别增加10.0%和18.5% (P < 0.05)，在250度/秒时分别增加16.7%和14.7% （P < 0.05）。转矩-速度关系曲线在训练结束时呈现向上位移，主要集中在低速高转矩区域。计算机断层扫描的大腿中部组成显示，总大腿面积（4.8%）、总肌肉面积（11.4%）和股四头肌面积（9.3%）增加（P < 0.01）。股外侧肌活检显示I型纤维面积（33.5%）和II型纤维面积（27.6%）增加（P < 0.001）。日尿3-甲基- l-组氨酸排泄量随训练增加平均增加40.8% （P < 0.05）。老年男性的力量增加与显著的肌肉肥大和肌原纤维蛋白周转增加有关。
The effects of strength conditioning on skeletal muscle function and mass were determined in older men. Twelve healthy untrained volunteers (age range 60-72 yr) participated in a 12-wk strength training programs (8 repetitions/set; 3 sets/day; 3 days/wk) at 80% of the one repetition maximum (1 RM) for extensors and flexors of both knee joints. They were evaluated before the program and after 6 and 12 wk of training. Weekly measurements of 1 RM showed a progressive increase in strength in extensors and flexors. By 12 wk extensor and flexor strength had increased 107.4 (P < 0.0001) and 226.7% (P < 0.0001), respectively. Isokinetic peak torque of extensors and flexors measured on a Cybex II dynamometer increased 10.0 and 18.5% (P < 0.05) at 60.degree./s and 16.7 and 14.7% (P < 0.05) at 250.degree./s. The torque-velocity relationship showed an upward displacement of the curve at the end of training, mainly in the slow-velocity high-torque region. Midthigh composition from computerized tomographic scans showed an increase (P < 0.01) in total thigh area (4.8%), total muscle area (11.4%), and quadriceps area (9.3%). Biopsies of the vastus lateralis muscle revealed similar increases (P < 0.001) in type I fiber area (33.5%) and type II fiber area (27.6%). Daily excretion of urinary 3-methyl-L-histidine increased with training (P < 0.05) by an average 40.8%. Strength gains in older men were associated with significant muscle hypertrophy and an increase in myofibrillar protein turnover.