Eosinophilic Esophagitis.
Eosinophilic Esophagitis.
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DOI：
10.1056/nejmra1502863
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发表时间：
2015-10-22
期刊：
影响因子：
--
通讯作者：
Katzka DA
中科院分区：
文献类型：
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作者：
Furuta GT;Katzka DA
嗜酸性食管炎曾经被认为是一种罕见的疾病，现在是在评估儿童喂养问题和评估成人吞咽困难和食物嵌塞期间诊断的最常见疾病之一。该实体存在于世界各地，但在西方国家进行了最广泛的研究，估计其患病率在所有儿童和成人中为0.4%。嗜酸性食管炎是否真的是一种新的疾病或仅仅是一个最近认识到的尚不确定。在这篇综述中，我们考虑的诊断标准，病理生理和临床特征，以及治疗这种日益流行的疾病。
Once considered a rare condition, eosinophilic esophagitis is now one of the most common conditions diagnosed during the assessment of feeding problems in children and during the evaluation of dysphagia and food impaction in adults. The entity exists worldwide but has been most extensively studied in Western countries, where its prevalence has been estimated to be 0.4% among all children and adults. Whether eosinophilic esophagitis is truly a new disease or simply a recently recognized one is uncertain. In this review, we consider the diagnostic criteria, pathophysiological and clinical features, and treatment of this increasingly prevalent disease.