A modified approach to determine the six cardiac bidomain conductivities.
A modified approach to determine the six cardiac bidomain conductivities.
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DOI：
10.1016/j.compbiomed.2021.104549
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发表时间：
2021-08
影响因子：
7.7
通讯作者：
中科院分区：
文献类型：
--
作者：
六个心脏bidomain电导率的准确值是至关重要的有意义的计算研究的心脏组织中的传导，还有待确定的实验手段。虽然以前的研究已经提出了一种方法，使用多电极阵列来测量电位，从其中可以确定的电导率，它已被发现，电导率不能检索一致时，在电位的噪声变化。本文提出了一种协议，它不仅已被证明可以检索到一个合理的精度的电导率，但这样做的存在下，一个更合适的加性高斯噪声模型，同时使用更少的计算资源。通过重复该方案，将两个预制的128个电极阵列（一个阵列具有正方形电极排列，另一个阵列具有矩形排列）与先前研究中提出的75个电极阵列进行比较。结果表明，与75个电极阵列相比，两个预制阵列通常更能够以更高的准确度获得心脏电导率。128个电极的矩形阵列被定向为使得阵列的长度首先沿着纤维的方向延伸，然后被重新定向为使得阵列的长度垂直于纤维的方向延伸。128电极矩形阵列，以这种方式定向时，更能够检索的电导率比其余的阵列测试，因此，我们建议这种安排在实验试验期间使用。
Accurate values for the six cardiac bidomain conductivities are crucial for meaningful computational studies of conduction in cardiac tissue, and are yet to be determined by experimental means. Although previous studies have proposed an approach using a multi-electrode array to measure potentials, from which the conductivities can be determined, it has been found that the conductivities cannot be retrieved consistently when the noise in the potentials varies. This paper presents a protocol, which not only has been shown to retrieve the conductivities to a reasonable accuracy, but does so under the presence of a more appropriate additive Gaussian noise model, while using fewer computational resources. Through repetitions of the protocol, a comparison of two pre-fabricated 128 electrode arrays, one array with a square arrangement of electrodes and the other with a rectangular arrangement, was made against a 75-electrode array proposed in previous studies. Results indicated that the two pre-fabricated arrays were generally more capable of obtaining the cardiac conductivities to a higher degree of accuracy than the 75-electrode array. The 128-electrode rectangular array was orientated such that the length of the array first ran along the direction of the fibres, then was reorientated such that the length of the array ran perpendicular to the direction of the fibres. The 128-electrode rectangular array, when orientated in this manner, was more capable of retrieving the conductivities than the remainder of the arrays tested, and thus we suggest this arrangement be used during experimental trials.
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DOI：
10.1152/ajpheart.1997.272.5.h2466
发表时间：
1997-05-01
影响因子：
4.8
作者：
LeGrice, IJ;Hunter, PJ;Smaill, BH
通讯作者：
Smaill, BH
影响因子：
3
作者：
Brunton, Bingni W.;Johnson, Lise A.;Kutz, J. Nathan
通讯作者：
Kutz, J. Nathan
影响因子：
3.8
作者：
Hopenfeld, B;Stinstra, JG;MacLeod, RS
通讯作者：
MacLeod, RS
影响因子：
3.2
作者：
Graham, B. M.;Adler, A.
通讯作者：
Adler, A.
影响因子：
3.8
作者：
Johnston, Barbara M.;Johnston, Peter R.;Kilpatrick, David
通讯作者：
Kilpatrick, David