Prognostic value of gastric intramucosal pH in critically ill children
Prognostic value of gastric intramucosal pH in critically ill children
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DOI：
10.1097/00003246-199806000-00039
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发表时间：
1998-06-01
影响因子：
8.8
通讯作者：
Ruiz-López, MJ
中科院分区：
文献类型：
--
作者：
Casado-Flores, J;Mora, E;Ruiz-López, MJ
目的：探讨血压计测定的胃粘膜内pH （pHi）与危重患儿多器官功能障碍综合征（MODS）发生及死亡的关系。设计：前瞻性观察性研究。环境：儿童教学医院的儿科重症监护病房（ICU）。患者：51例危重患儿（中位年龄5.4±5 [SD]岁，年龄范围1个月至16岁），诊断为：大手术后（26例）、脓毒症（8例）、多发创伤（5例）、急性呼吸窘迫综合征（4例）、杂症（8例）。干预措施：放置血压计导管，测量方法及主要结果：在儿童ICU住院期间，每天收集患儿入院时及pHi的儿童死亡风险（PRISM）评分及临床资料，使用乙状结肠血压计测定pHi，使用无条件logistic回归分析pi-ii的预后价值。入院时，26例患者出现低胃pHi（小于或等于7.35），其中17例患者的值为
Objective: To determine the association of tonometrically measured gastric intramucosal pH (pHi) to the occurrence of multiple organ dysfunction syndrome (MODS) and death in critically ill children.Design: Prospective, observational study.Setting: Pediatric intensive care unit (ICU) of a teaching children's hospital.Patients: Fifty-one critically ill children admitted (median age 5.4 +/- 5 [SD] yrs; range 1 mo to 16 yrs) with the following diagnoses: post major surgery (n = 26), sepsis (n = 8), multiple trauma (n = 5), acute respiratory distress syndrome (n = 4), and "miscellaneous" (n=8).Interventions: Placement of a tonometric catheter,Measurements and Main Results: Pediatric Risk of Mortality (PRISM) score and clinical data were collected on admission and pHi daily during their stay in the pediatric ICU, A sigmoid tonometer was used to determine the pHi, Unconditional logistic regression was used to investigate the prognostic value of pi-ii,On admission, 26 patients presented with low gastric pHi (less than or equal to 7.35) and 17 of them had values of