Potential role of computers in clinical investigation and management of diabetes mellitus.
Potential role of computers in clinical investigation and management of diabetes mellitus.
复制标题
计算机在糖尿病临床研究和管理中的潜在作用。
作者：
D. Rodbard
计算机可能在糖尿病患者的临床研究和管理中发挥越来越重要的作用。这些应用主要分为四个领域：1）诊所、医院和研究中心的数据库系统，以便于对患者的监视和数据分析; 2）医生和患者使用的个人微型计算机，用于存储、分析和传输数据; 3）便携式设备，用于提供关于患者使用的胰岛素剂量的建议;以及4）配备有存储器的血糖仪，其提供经验证的数据并且具有相关的软件，该软件具有用于复杂的图形和统计分析以及趋势检测的能力。基于存储器的血糖仪和个人微型计算机的重要产物是动态血糖曲线（AGP）。这是全天葡萄糖平均模式的显示，通常基于2周的数据。AGP显示每小时或与膳食相关的中位血糖、范围以及第25和第75次血糖。通过在存在大的随机变化的情况下进行信号平均，该显示可以揭示在个别日子不明显的模式。
Computers are likely to play an increasingly important role in the clinical investigation and management of patients with diabetes. The applications fall primarily into four areas: 1) data-base systems in clinics, hospitals, and research centers to facilitate surveillance of patients and analysis of data; 2) personal microcomputers for use by physicians and patients in storing, analyzing, and transmitting data; 3) portable devices to provide recommendations regarding insulin dose for patient use; and 4) memory-equipped glucose meters that provide verified data and have associated software with the capacity for sophisticated graphic and statistical analysis and detection of trends. An important outgrowth of the memory-based meter and the personal microcomputer is the ambulatory glucose profile (AGP). This is a display of the average pattern of glucose throughout the day, usually based on data from a 2-wk period. The AGP shows the median blood glucose, range, and 25th and 75th percentiles for each hour or in relationship to meals. By virtue of signal averaging in the presence of large random variability, this display may reveal patterns that are not evident on individual days.