Full genome sequences of torque teno sus virus strains that coinfected a pig with postweaning multisystemic wasting syndrome in Japan: implications for genetic diversity.

Full genome sequences of torque teno sus virus strains that coinfected a pig with postweaning multisystemic wasting syndrome in Japan: implications for genetic diversity.
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日本扭力特诺猪病毒株的全基因组序列,该病毒株使一头猪同时感染断奶后多系统消耗综合症:对遗传多样性的影响。

DOI:
10.1007/s00705-015-2593-x
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发表时间:
2015
期刊:
Arch Virol.
影响因子:
--
通讯作者:
Deguchi E.
Deguchi E.
中科院分区:
--
文献类型:
--
作者:
Ozawa M;Kawabata T;Okuya K;Nagano K;Kanda T;Kanazawa N;Tsukiyama-Kohara K;Taneno A;Deguchi E.

文献摘要

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我们确定了在日本断奶后多系统衰竭综合征(PMWS)猪和健康猪中检测到的细扭转病毒(TTSuVs)的全基因组序列。出乎意料的是,我们发现在日本的PMWS感染猪与一株TTSuV1,五株TTSuV2和一株PCV 2共感染。对这些毒株进行全基因组测序,然后进行系统发育分析,发现感染PMWS感染猪的TTSuV2毒株具有广泛的遗传多样性。这些结果表明,地理偏见的可用遗传信息TTSuVs的遗传多样性的评估有有限的影响。
We determined the complete genome sequences of torque teno sus viruses (TTSuVs) detected in pigs with postweaning multisystemic wasting syndrome (PMWS) and in healthy pigs in Japan. Unexpectedly, we found coinfection of a PMWS-affected pig in Japan with one strain of TTSuV1, five strains of TTSuV2, and one strain of PCV2. Full-genome sequencing of each of these strains, followed by phylogenetic analysis, revealed broad genetic diversity in the TTSuV2 strains infecting the PMWS-affected pig. These results suggest that the geographical bias in the available genetic information about TTSuVs has a limited impact on the evaluation of their genetic diversity.