NONPARAMETRIC ANALYSIS OF TRUNCATED SURVIVAL-DATA, WITH APPLICATION TO AIDS
NONPARAMETRIC ANALYSIS OF TRUNCATED SURVIVAL-DATA, WITH APPLICATION TO AIDS
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DOI：
10.2307/2336602
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发表时间：
1988-09-01
期刊：
影响因子：
2.7
通讯作者：
DEGRUTTOLA, V
中科院分区：
文献类型：
--
作者：
LAGAKOS, SW;BARRAJ, LM;DEGRUTTOLA, V
艾滋病的诱导分布的数据来源之一来自因受污染的输血而感染艾滋病病毒的人。对这些数据的分析是复杂的，因为输血感染的人数是未知的;只有那些在一定的时间间隔内感染并发展成艾滋病的人才有信息。统计问题是一个关于传染病和疾病的随机过程的推断，其实现在时间上是正确的。通过考虑逆时过程，我们将问题转化为分析在内部时间截断的生存数据。我们开发的非参数方法估计和比较几组的感应分布的可识别方面。
One source of data for the induction distribution of AIDS arises from persons infected by the AIDS virus from contaminated blood transfusions. Analyses of these data are complicated because the number of individuals infected by transfusion is unknown; information is available only for those who are infected and develop AIDS within a certain chronologic time interval. The statistical problem is one of making inferences about a stochastic process of infection and disease for which realizations are right truncated in chronologic time. By considering the process in reverse time, we transform the problem to one of analysing survival data that are left truncated in internal time. We develop nonparametric methods for estimating and comparing the identifiable aspects of the induction distributions of several groups.