Morphologic expression of the left coronary artery in pigs. An approach in relation to human heart
Morphologic expression of the left coronary artery in pigs. An approach in relation to human heart
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DOI：
10.5935/1678-9741.201400270
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发表时间：
2014-04-01
影响因子：
1.3
通讯作者：
Ballesteros, Luis Ernesto
中科院分区：
文献类型：
--
作者：
Gómez, Fabian Alejandro;Ballesteros, Luis Ernesto
前言：尽管左冠状动脉是一种重要的实验模型，但有关猪左冠状动脉的资料很少。目的：确定猪左冠状动脉的形态特征。方法：对158例猪心进行评价。插管后，左冠状动脉内注入合成树脂。结果：左冠状动脉内径为6.98±1.56 mm，长度为3.51±0.99 mm。79%的病例分叉为室间前动脉和旋支动脉，21%的病例为三分叉，存在斜角动脉。室间前动脉终止于心尖者占79.7%，旋支动脉终止于左室后侧者占79.7%，未达后室间沟者占79.7%。7.6%的标本室间前动脉终支与后室间动脉终支吻合。89.9%的心脏出现室间前动脉前上支。87.9%的猪存在左边缘支，直径为2.25+/-0.55 mm。结论：与人相比，猪的左冠状动脉主干和分支较短，甚至回旋支从未到达后室间沟。我们的发现对实验血流动力学和操作模型的设计是有用的。
Introduction: In spite of its importance as an experimental model, the information on the left coronary artery in pigs is sparse.Objective: To determine the morphologic features of the left coronary artery in pigs.Methods: We evaluated 158 pig hearts. The left coronary artery was perfused with synthetic resin after their ostia had been catheterized. Diameters and courses of the vascular beds were measured with an electronic caliper (Mitutoyo (R)).Results: The diameter of left coronary artery was 6.98 +/- 1.56 mm and its length was 3.51 +/- 0.99 mm. It was found to end up by bifurcating itself into the anterior interventricular artery and the circumflex artery in 79% of the cases, and by trifurcating in 21% of the cases, with the presence of the diagonal artery. The anterior interventricular artery ended up at the apex in 79.7% of the cases, and the circumflex artery at the posterior aspect of the left ventricle in 64% of the case, this artery never reached the posterior interventricular sulcus. An anastomosis between the terminal branches of the anterior interventricular artery and the posterior interventricular artery was found in 7.6% of the specimens. The antero-superior branch of the anterior interven-tricular artery occurred in 89.9% of the hearts. A left marginal branch was observed in 87.9% of the cases with a diameter of 2.25 +/- 0.55 mm.Conclusion: Compared with humans, pigs have shorter left coronary artery trunks and branches; even the circumflex artery never reaches the posterior interventricular sulcus. Our findings are useful for the design of experimental hemodynamic and procedural models.