Mitral Annular Dynamics and Left Ventricular Diastole.
Mitral Annular Dynamics and Left Ventricular Diastole.
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DOI：
10.14740/cr602w
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发表时间：
2017-10
影响因子：
1.9
通讯作者：
Lopez Menendez F
中科院分区：
文献类型：
--
作者：
Lopez-Candales A;Hernandez-Suarez DF;Lopez Menendez F
尽管使用组织多普勒成像（TDI）对二尖瓣环（MA）进行舒张期询问在评估左心室（LV）舒张功能方面非常有用，但先前周期MA收缩期位移或速度分量对随后LV舒张的相对贡献尚未研究。因此，我们试图确定MA收缩动力学和LV舒张功能参数之间的关联。对于这项回顾性研究，我们的分析仅包括具有良好左心房（LA）和LV腔室内膜边界分辨率的完整超声心动图（M模式（MAPSE））和外侧MA的组织多普勒（MA TDI S '）以及用于评估LV腔室的完整多普勒数据。100例患者（平均年龄54 ± 14岁）的测量结果表明，二尖瓣环收缩期位移和速度与左室射血分数相关（P < 0.05）。只有MA位移与年龄和LV质量相关。最重要的是，未发现MAPSE与LV舒张末期压之间存在相关性。然而，在鲜明的对比，MA TDI S'与MA舒张速度在早期和晚期LV舒张期。尽管MAPSE和MA TDI S'是LV射血分数的替代指标，但只有MA TDI S'与舒张期MA速度相关，因为MAPSE与LV射血分数指标之间没有相关性。现在有必要进行更多的研究来探讨MA TDI S'降低是否会影响LV舒张功能障碍患者的症状特征或总体预后。
Though diastolic interrogation of the mitral annulus (MA) using tissue Doppler imaging (TDI) has been quite useful in assessing left ventricular (LV) diastolic function, the relative contribution of the previous cycle MA systolic displacement or velocity components to subsequent LV diastole has not been previously investigated. We therefore sought to determine the association between MA systolic dynamics and LV diastolic function parameters. For this retrospective study, only complete echocardiograms having good endocardial border resolution of both left atrial (LA) and LV chambers with M-mode (MAPSE) and tissue Doppler of the lateral MA (MA TDI S’) as well as complete Doppler data to perform assessment of LV diastole were included in our analysis. Data from 100 patients (mean age 54 ± 14) showed that both MA systolic displacement and velocity correlate with LV ejection fraction (P < 0.05). Only MA displacement was associated with age and LV mass. Most importantly no correlation was found between MAPSE and LV diastole. However, in sharp contrast MA TDI S’ correlated with MA relaxation velocities during both early and late LV diastole. Even though MAPSE and MA TDI S’ are surrogate measures of LV ejection fraction, only MA TDI S’ correlates with diastolic MA velocities as no correlation was identified between MAPSE and measures of LV diastole. Additional studies are now warranted to explore whether a reduced MA TDI S’ may affect the symptomatic profile or the overall prognosis of patients with LV diastolic dysfunction.