Mating competitiveness and life-table comparisons between transgenic and Indian wild-type Aedes aegypti L.
Mating competitiveness and life-table comparisons between transgenic and Indian wild-type Aedes aegypti L.
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DOI：
10.1002/ps.3873
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发表时间：
2015-07
影响因子：
4.1
通讯作者：
Alphey L
中科院分区：
文献类型：
--
作者：
Patil PB;Reddy BP;Gorman K;Reddy KV;Barwale SR;Zehr UB;Nimmo D;Naish N;Alphey L
OX513A 是一种基因工程埃及伊蚊菌株，携带可抑制的显性遗传转基因，可赋予未成熟杂合后代致死性。释放的雄性 OX513A 成虫已被证明对局部抑制野生伊蚊有效。埃及伊蚊，强调了其在病媒控制方面的潜力。使用交配和生命表评估来比较 OX513A 与饲养的 Ae。从印度新德里和奥兰加巴德地区收集的埃及伊蚊菌株。 OX513A或新德里品系的新德里雌性与雄性的交配比例分别为0.52和0.48，表明雌性对这两种品系没有歧视，并且两种品系的雄性具有同等的竞争性。 OX513A从一龄到成虫羽化的发育时间（10.7±0.04天）明显长于新德里品系（9.4±0.04天）和奥兰加巴德品系（9.1±0.04天）。品系之间的平均寿命、雌性生殖参数和种群增长参数的差异不显着。实验室研究表明，OX513A 和印度伊蚊之间仅存在具有有限生物学相关性的微小生命表差异。埃及伊蚊种群和雄性在交配竞争力方面具有同等潜力。因此，结果支持 OX513A 菌株作为持续评估伊蚊可持续管理的合适候选菌株。印度的埃及伊蚊种群。 © 2014 Gangabishan Bhikulal 投资贸易有限公司。 《害虫管理科学》由 John Wiley & Sons Ltd 代表化学工业协会出版。
OX513A is a genetically engineered strain of Aedes aegypti carrying a repressible, dominantly inherited transgene that confers lethality in immature heterozygous progeny. Released male OX513A adults have proven to be effective for the localised suppression of wild Ae. aegypti, highlighting its potential in vector control. Mating and life-table assessments were used to compare OX513A with reared Ae. aegypti strains collected from New Delhi and Aurangabad regions in India. Mating proportions of New Delhi females versus males of OX513A or New Delhi strains were 0.52 and 0.48 respectively, indicating no discrimination by females against either strain, and males of both strains were equally competitive. Developmental time from first instar to adult emergence was significantly longer for OX513A (10.7 ± 0.04 days) than for New Delhi (9.4 ± 0.04 days) and Aurangabad strains (9.1 ± 0.04 days). Differences in mean longevities, female reproductive parameters and population growth parameters between the strains were non-significant. The laboratory study demonstrates that only minor life-table variations of limited biological relevance exist between OX513A and Indian Ae. aegypti populations, and males had equal potential for mating competitiveness. Thus, results support the OX513A strain as a suitable candidate for continued evaluation towards sustainable management of Ae. aegypti populations in India. © 2014 Gangabishan Bhikulal Investment and Trading Limited. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.