Measurement issues in the use of cognitive neuroscience tasks in drug development for impaired cognition in schizophrenia: A report of the second consensus building conference of the CNTRICS initiative
Measurement issues in the use of cognitive neuroscience tasks in drug development for impaired cognition in schizophrenia: A report of the second consensus building conference of the CNTRICS initiative
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DOI：
10.1093/schbul/sbn037
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发表时间：
2008-07-01
影响因子：
6.6
通讯作者：
Carter, Cameron S.
中科院分区：
文献类型：
--
作者：
Barch, Deanna M.;Carter, Cameron S.
本综述描述了作为认知神经科学治疗研究改善精神分裂症认知（CNTRICS）倡议的一部分的第二次会议的目标和目的。第二次会议由一系列在线调查提供信息，并汇集了来自学术界和工业界的基础和临床科学家，以解决每个研究领域的核心问题。我们的目标是为未来的研究提出建议，解决将认知神经科学范式转化为治疗发现和开发过程中可行的任务所涉及的心理测量学和实践挑战。在这篇概述文章中，我们描述了会议上的一系列演讲。本文是本期特刊所载一系列文章的介绍，这些文章概述和讨论了在这些会谈和随后的会议讨论中提出的问题和建议。此外，我们描述了在会议前一个月进行的在线调查，这些调查用于从该领域获得关于重要任务选择标准的建议，并为认知神经科学任务的心理测量学发展产生初步基准目标。
This overview describes the goals and objectives of the second conference conducted as part of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. This second conference was informed by a series of online surveys and brought together basic and clinical scientists from academia and industry to address the concerns central to each field of research. Our goal was to develop recommendations for future research addressing the psychometric and practical challenges involved in translating paradigms from cognitive neuroscience into tasks that are feasible for use in the treatment discovery and development process. In this overview article, we describe the series of talks that were presentations at the conference. This article serves as an introduction to the set of articles included in this special issue that provide overviews and discussions of the issues raised and the recommendations made in these talks and in the subsequent discussions at the meeting. In addition, we describe the online surveys conducted in the month before the conference that were used to obtain suggestions from the field as to important task selection criteria and to generate initial benchmark goals for psychometric development for cognitive neuroscience tasks.