Prediction of the migration behavior of organic acids in micellar electrokinetic chromatography.
Prediction of the migration behavior of organic acids in micellar electrokinetic chromatography.
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DOI：
10.1016/0021-9673(93)80042-7
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发表时间：
1993-02
期刊：
影响因子：
--
通讯作者：
S. C. Smith;M. Khaledi
中科院分区：
文献类型：
--
作者：
S. C. Smith;M. Khaledi
定量地研究了同系酚类化合物在胶束电动色谱中的迁移行为。该模型根据每种溶质的基本物理和化学常数（酸解离常数Ka、胶束结合常数Km、缓冲液的pH和缓冲液中的胶束浓度（[M]））描述迁移率。该模型用于预测每个溶质在二维pH/[M]空间的流动性。预测和实际电泳图显示了这种技术的实用性。
The migration behavior of an homologous series of phenols in micellar electrokinetic chromatography is quantitatively presented. This model describes mobility in terms of fundamental physical and chemical constants of each solute (acid dissociation constantKa, micelle binding constantKm, the pH of the buffer, and the micelle concentration ([M]) in the buffer. The model was used to predict the mobility of each solute over a two-dimensional pH/[M] space. Predicted and actual electropherograms show the usefulness of this technique.