The burden of vancomycin-resistant enterococcal infections in US hospitals, 2003 to 2004
The burden of vancomycin-resistant enterococcal infections in US hospitals, 2003 to 2004
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DOI：
10.1016/j.diagmicrobio.2008.04.013
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发表时间：
2008-09-01
影响因子：
2.9
通讯作者：
McDonald, L. Clifford
中科院分区：
文献类型：
--
作者：
Reik, Rebecca;Tenover, Fred C.;McDonald, L. Clifford
尽管卫生保健界对万古霉素耐药肠球菌（VRE）非常关注，但没有估计每年在美国医院发生的VRE感染总数。利用来自全国出院调查和全国抗菌素耐药性监测系统的数据，我们估计了美国每年因VRE血流、尿路和伤口或腹腔内感染住院的人数。由于出院诊断编码的不精确性，我们通过使用各种数据源对VRE感染住院进行了保守和自由估计。对于2003年和2004年，我们保守估计有20 777和20 93 1 VRE感染，分别为这些相同的年份，自由估计分别为78 330和85 586。由于有如此大量的出院病例，其感染编码没有微生物编码，因此保守估计可能低估了真正的负担。这些估计强调了控制VRE的重要性，以及需要开发更好的方法来跟踪此类感染的负担。爱思唯尔公司出版
Despite significant concern in the health care community regarding vancomycin-resistant enterococci (VRE), there are no estimates of the total number of VRE infections that occur each year in US hospitals. Using data from a national Survey of hospital discharges and a national antimicrobial resistance surveillance system, we estimated the annual number of US hospitalization with VRE bloodstream, urinary tract, and wound or intra-abdominal infections. Because of the inexact nature of hospital discharge diagnosis coding, we made both a conservative and liberal estimate of hospitalization with VRE infection by using a variety of data Sources. For the years 2003 and 2004, we conservatively estimated that there were 20 777 and 20 93 1 VRE infections, respectively; for those same years, the liberal estimates were 78 330 and 85 586, respectively. Because there are Such a large number of hospital discharges for which an infection is coded without an organism code, it is likely that the conservative estimate is an underestimate of the true burden. These estimates highlight the importance of controlling VRE and the need to develop improved methods for tracking the burden of such infections. Published by Elsevier Inc.