ORGANOLEAD-MEDIATED ARYLATION OF ALLYL BETA-KETOESTERS - A SELECTIVE SYNTHESIS OF ISOFLAVANONES AND ISOFLAVONES
ORGANOLEAD-MEDIATED ARYLATION OF ALLYL BETA-KETOESTERS - A SELECTIVE SYNTHESIS OF ISOFLAVANONES AND ISOFLAVONES
复制标题
DOI：
10.1039/p19930001729
复制
发表时间：
1993-08-07
期刊：
影响因子：
--
通讯作者：
RATTIGAN, BA
中科院分区：
文献类型：
--
作者：
DONNELLY, DMX;FINET, JP;RATTIGAN, BA
A-环取代和未取代的3-烯丙氧基羰基色满-4-酮与芳基铅（IV）三乙酸酯的芳基化，然后选择性催化脱烯丙氧基羰基化，以高的总产率得到异黄烷酮或异黄酮。在5，7-二甲氧基苯并二氢吡喃-4-酮与更受阻的2，4，6-三甲氧基苯基三乙酸铅的反应中观察到芳基化步骤中的最高产率。
Arylation of A-ring substituted and unsubstituted 3-allyloxycarbonylchroman-4-ones with aryllead(IV) triacetates followed by selective catalytic deallyloxycarbonylation affords isoflavanones or isoflavones in high overall yields. The highest yield in the arylation step was observed in the reaction of 5,7-dimethoxychroman-4-one with the more hindered 2,4,6-trimethoxyphenyllead triacetate.