Monte Carlo (MC) study of dose distribution and Cherenkov imaging in total skin electron therapy (TSET) with TOPAS.
Monte Carlo (MC) study of dose distribution and Cherenkov imaging in total skin electron therapy (TSET) with TOPAS.
复制标题
使用 TOPAS 进行全皮肤电子治疗 (TSET) 中剂量分布和切伦科夫成像的蒙特卡罗 (MC) 研究。
DOI:
10.1117/12.2583397
复制
发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Zhu,Timothy
中科院分区:
文献类型:
--
作者:
Zhong,Weili;Ong,YiHong;Zhu,Timothy
Malignant tissues can be effectively treated by Total Skin Electron Therapy (TSET) over the entire body surface using 6 MeV electron beams. During the radiation treatment, Cherenkov photons are emitted from the patient’s skin, and can potentially be used for in-vivo imaging of the radiation dose distribution. A Monte Carlo (MC) simulation toolkit TOPAS is used to study the generation and propagation of Cherenkov photons that are generated from the interaction of electron radiation with human tissues, and to understand the relationship between the dose distributions and the Cherenkov photon distributions. Validation of MC simulations with experiments are performed at 100 SSD and 500 SSD, and simulations of a patient phantom in realistic clinical treatment setups have been done. These simulations with TOPAS show that the emitted Cherenkov distributions at phantom surfaces closely follow their corresponding dose distributions.
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DOI:
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发表时间:
1987
期刊:
影响因子:
--
作者:
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通讯作者:
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影响因子:
4.8
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1954
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1981
期刊:
Biochemical and Biophysical Research Communications - BBRC
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通讯作者:
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