Continuous High-Throughput Fabrication of Architected Micromaterials via In-Air Photopolymerization
Continuous High-Throughput Fabrication of Architected Micromaterials via In-Air Photopolymerization
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DOI：
10.1002/adma.202006336
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发表时间：
2020-12-04
影响因子：
29.4
通讯作者：
Visser, Claas Willem
中科院分区：
文献类型：
--
作者：
Jiang, Jieke;Shea, Gary;Visser, Claas Willem
光学编码、药物输送、诊断、组织工程、剪切诱导凝胶和功能工程流变学的最新进展很大程度上依赖于具有可调形状、尺寸和成分的微粒和微纤维。然而，所需复杂微材料的可扩展制造仍然是一个长期存在的挑战。这里，液体射流的空气聚合被证明是一种新颖的平台，可以在高通量（每个喷嘴> 100 mL h(-1)）下生产尺寸、形状和成分可调的微粒和微纤维。聚合动力学被定量研究并建模为墨水成分、紫外光强度和液体射流速度的函数，从而能够在喷射状态下设计复杂的微材料。微材料的尺寸、形态和局部化学性质是独立控制的，这一点通过使用 5 种不同的光聚合物以及多材料复合材料生产微材料来强调。同时优化这些控制参数可以快速制造用作软执行器的刺激响应 Janus 纤维。最后，空气中的光聚合可以控制打印液滴的曲率，焦距可调的微透镜的高通量打印就凸显了这一点。快速处理与成分和结构可调性的结合，为定制微材料在软物质、医学、制药和光学领域的应用开辟了一条新途径。
Recent advances in optical coding, drug delivery, diagnostics, tissue engineering, shear-induced gelation, and functionally engineered rheology crucially depend on microparticles and microfibers with tunable shape, size, and composition. However, scalable manufacturing of the required complex micromaterials remains a long-standing challenge. Here in-air polymerization of liquid jets is demonstrated as a novel platform to produce microparticles and microfibers with tunable size, shape, and composition at high throughput (>100 mL h(-1) per nozzle). The polymerization kinetics is quantitatively investigated and modeled as a function of the ink composition, the UV light intensity, and the velocity of the liquid jet, enabling engineering of complex micromaterials in jetting regimes. The size, morphology, and local chemistry of micromaterials are independently controlled, as highlighted by producing micromaterials using 5 different photopolymers as well as multi-material composites. Simultaneous optimization of these control parameters yields rapid fabrication of stimuli-responsive Janus fibers that function as soft actuators. Finally, in-air photopolymerization enables control over the curvature of printed droplets, as highlighted by high-throughput printing of microlenses with tunable focal distance. The combination of rapid processing and tunability in composition and architecture opens a new route toward applications of tailored micromaterials in soft matter, medicine, pharmacy, and optics.