Assessing and Mitigating Bias in Medical Artificial Intelligence The Effects of Race and Ethnicity on a Deep Learning Model for ECG Analysis

Assessing and Mitigating Bias in Medical Artificial Intelligence The Effects of Race and Ethnicity on a Deep Learning Model for ECG Analysis
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DOI:
10.1161/circep.119.007988
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发表时间:
2020-03-01
影响因子:
8.4
通讯作者:
Lopez-Jimenez, Francisco
Lopez-Jimenez, Francisco
中科院分区:
医学1区
文献类型:
--
作者:
Noseworthy, Peter A.;Attia, Zachi, I;Lopez-Jimenez, Francisco

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Background:Deep learning algorithms derived in homogeneous populations may be poorly generalizable and have the potential to reflect, perpetuate, and even exacerbate racial/ethnic disparities in health and health care. In this study, we aimed to (1) assess whether the performance of a deep learning algorithm designed to detect low left ventricular ejection fraction using the 12-lead ECG varies by race/ethnicity and to (2) determine whether its performance is determined by the derivation population or by racial variation in the ECG.Methods:We performed a retrospective cohort analysis that included 97 829 patients with paired ECGs and echocardiograms. We tested the model performance by race/ethnicity for convolutional neural network designed to identify patients with a left ventricular ejection fraction