Altered Leukocyte Responsiveness in Dairy Cows with Naturally Occurring Chronic Staphylococcus aureus Mastitis
Altered Leukocyte Responsiveness in Dairy Cows with Naturally Occurring Chronic Staphylococcus aureus Mastitis
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DOI：
10.1292/jvms.10-0379
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发表时间：
2011-07-01
影响因子：
1.2
通讯作者：
Chang, Chai J.
中科院分区：
文献类型：
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作者：
Nagahata, Hajime;Kawai, Hiroatsu;Chang, Chai J.
通过检测天然慢性金黄色葡萄球菌(S.（石蕊）乳腺炎奶牛与健康奶牛的炎症参数、白细胞表面标志物、白细胞功能反应和细胞因子mRNA表达的变化，探讨乳腺白细胞对金黄色葡萄球菌感染的反应。牛奶中炎症参数和基质金属蛋白酶活性的升高揭示了奶牛慢性乳腺炎的特征。金黄色葡萄球菌乳腺炎奶牛乳中l -选择素和CD18分子对中性粒细胞的表达及CD8细胞比例的影响显著(P
Changes in inflammatory parameters, leukocyte surface markers, functional responses and cytokine mRNA expression of leukocytes of dairy cows with naturally occurring chronic Staphylococcus aureus (S. (litmus) mastitis and healthy cows were determined to elucidate the leukocyte responses to S. aureus infection of the mammary gland. Increased values in inflammatory parameters and matrix metalloproteinase activities in milk revealed the characteristics of cows with chronic mastitis. Expression of L-selectin and CD18 molecules on neutrophils and proportion of CD8 cells in milk from cows with S. aureus mastitis were significantly (P