LOCALIZATION OF LACTOFERRIN IN THE MALE REPRODUCTIVE-TRACT
LOCALIZATION OF LACTOFERRIN IN THE MALE REPRODUCTIVE-TRACT
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DOI：
10.1111/j.1365-2605.1989.tb01302.x
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发表时间：
1989-06-01
影响因子：
--
通讯作者：
TUOHIMAA, P
中科院分区：
文献类型：
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作者：
WICHMANN, L;VAALASTI, A;TUOHIMAA, P
采用过氧化物酶-抗过氧化物酶方法在光镜和电镜水平上研究了乳铁蛋白在正常人前列腺、精囊、输精管、附睾和睾丸中的免疫组织化学定位。乳铁蛋白免疫反应性位于前列腺和精囊的腺上皮细胞和粒细胞中。在前列腺中，乳铁蛋白分布不均匀；一些腺体仅含有阳性细胞，另一些腺体则完全为乳铁蛋白阴性，而其余的则含有分散的阳性细胞。精囊分为三段，虽然是上皮性的，但其乳铁蛋白含量差异很大。输精管、附睾和睾丸不含乳铁蛋白。总之，在前列腺和精囊中发现了乳铁蛋白，但在睾丸中没有发现。
The immunohistochemical localization of lactoferrin in the normal human prostate, seminal vesicle, vas deferens, epididymis and testis was studied using the peroxidase-antiperoxidase method at the light and electron microscopical level. Lactoferrin immunoreactivity was localized in the glandular epithelial cells and granulocytes in the prostate and seminal vesicle. In the prostate, lactoferrin showed an uneven distribution; some of the glands contained exclusively positive cells and others were completely lactoferrin negative, while the rest contained scattered positive cells. The seminal vesicles were divided into three segments, and their lactoferrin content varied significantly although it was epithelial. The ductus deferens, epididymis and testis contained no lactoferrin. In conclusion, lactoferrin was found in the prostate and seminal vesicles, but not in the testis.