Taste isn't just for taste buds anymore.
Taste isn't just for taste buds anymore.
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DOI：
10.3410/b3-20
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Kinnamon SC
中科院分区：
文献类型：
--
作者：
Finger TE;Kinnamon SC
味觉是一种有区别的感觉，涉及口腔的专门受体细胞（味蕾）和至少两个不同的G蛋白偶联受体分子家族，它们检测营养重要的物质或潜在的毒素。然而，驱动味觉的受体机制也被全身的许多系统所利用。这些所谓的味觉感受器是如何以及为什么被用来调节消化和呼吸的，现在是一个深入研究的问题。在这篇文章中，我们提供了一个历史的角度来看，这些系统的概述，导致进一步研究的方向上的猜测。
Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste buds) and at least two distinct families of G protein-coupled receptor molecules that detect nutritionally important substances or potential toxins. Yet the receptor mechanisms that drive taste also are utilized by numerous systems throughout the body. How and why these so-called taste receptors are used to regulate digestion and respiration is now a matter of intense study. In this article we provide a historical perspective and an overview of these systems, leading to speculations on directions for further research.