Integration of fMRI, NIROT and ERP for studies of human brain function

Integration of fMRI, NIROT and ERP for studies of human brain function
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DOI:
10.1016/j.mri.2005.12.039
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发表时间:
2006-05-01
影响因子:
2.5
通讯作者:
Skudlarski, P
Skudlarski, P
中科院分区:
医学4区
文献类型:
--
作者:
Gore, JC;Horovitz, SG;Skudlarski, P

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与其他方法相比,评估人脑功能的不同方法具有特定的优点和缺点,但人们认为,将不同的方法结合起来将提供比单独获得更多的信息。例如,功能性磁共振成像(fMRI)具有良好的空间分辨率,但时间分辨率较差,而电生理记录(事件相关电位或ERP)则匡威。在最近的工作回顾中,我们强调了一种新的方法来结合这些模式的方式,旨在增加信息的起源和特定的ERP的发电机的位置和功能磁共振成像和ERP信号之间的关系。近红外成像技术也被研究作为功能磁共振成像的替代品,可以很容易地与同步电生理记录相结合。这些模态中的每一个原则上也可以用于所谓的稳态采集,其中可以分析来自大脑的信号的相关结构以提供对大脑功能的新见解。(c)2006年爱思唯尔公司All rights reserved.
Different methods of assessing human brain function possess specific advantages and disadvantages compared to others, but it is believed that combining different approaches will provide greater information than can be obtained from each alone. For example, functional magnetic resonance imaging (fMRI) has good spatial resolution but poor temporal resolution, whereas the converse is true for electrophysiological recordings (event-related potentials or ERPs). In this review of recent work, we highlight a novel approach to combining these modalities in a manner designed to increase information on the origins and locations of the generators of specific ERPs and the relationship between fMRI and ERP signals. Near infrared imaging techniques have also been studied as alternatives to fMRI and can be readily integrated with simultaneous electrophysiological recordings. Each of these modalities may in principle be also used in so-called steady-state acquisitions in which the correlational structure of signals from the brain may be analyzed to provide new insights into brain function. (c) 2006 Elsevier Inc. All rights reserved.