Ln(OTf)3-catalysed highly regioselective alcoholysis of 2,3-epoxy alcohols
Ln(OTf)3-catalysed highly regioselective alcoholysis of 2,3-epoxy alcohols
复制标题
Ln(OTf)3催化的2,3-环氧醇的高度区域选择性醇解
DOI：
10.1039/c8ob02448k
复制
发表时间：
2019
影响因子：
3.2
通讯作者：
Iwabuchi Yoshiharu
中科院分区：
文献类型：
--
作者：
Nakamura Daichi;Sasano Yusuke;Iwabuchi Yoshiharu
研究了Ln（OTf）3催化2，3-和3，4-环氧醇醇解反应的区域选择性，拓展了反应的范围。通过应用于4-丙氧基-5-羟基-2，3-戊二酮（C4-丙氧基-HPD）的构建来证明合成用途，所述4-丙氧基-HPD是AI-2群体感应中的有效合成介体。
Regioselectivity of Ln(OTf)3-catalysed alcoholysis of 2,3- and 3,4-epoxy alcohols was closely investigated to expand the scope of the transformations. The synthetic use was demonstrated by application to the construction of 4-propoxy-5-hydroxy-2,3-pentanedione (C4-propoxy-HPD), which is a potent synthetic mediator in AI-2 quorum sensing.