Wavefront analysis in eyes with nuclear or cortical cataract

Wavefront analysis in eyes with nuclear or cortical cataract
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DOI:
10.1016/s0002-9394(02)01402-2
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发表时间:
2002-07-01
影响因子:
4.2
通讯作者:
Mihashi, T
Mihashi, T
中科院分区:
医学1区
文献类型:
--
作者:
Kuroda, T;Fujikado, T;Mihashi, T

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目得:比较眼球高阶像差(全眼)和角膜轻度皮质或核性白内障的眼睛,并估计的影响,眼睛高阶像差的损失对比敏感度使用wavefront analysis.DESIGN:观察病例系列。对4例轻度核性白内障患者的6只眼、14例轻度皮质性白内障患者的18只眼和9例正常人的9只眼进行了检查。使用Hartmann-Shack(HS)像差仪测量中心直径为6 mm的眼球和角膜的波前像差。高阶像差用Zernike多项式计算,最高可达六阶。本文研究了Scheimpflug照相机测量的平均透镜密度(ALD)与眼总高阶像差(OTHA)之间的关系。对比敏感度(CS)和OTHA或ALD之间的关系也examined.Results:OTHA是显着较大的白内障与正常人相比,而角膜总高阶像差白内障和正常人之间没有差异。核性白内障的球差极性均为负,皮质性白内障的球差极性均为正。在白内障患者中,ALD与OTHA之间的相关性不显著。CS与OTHA高度相关,而与ALD中度相关。结论:HS像差仪可客观评价轻度白内障眼的像差,并揭示了核性白内障与皮质性白内障的球差极性不同。研究还表明,在轻度核性或皮质性白内障中,不仅光散射,而且透镜的光学像差也有助于对比敏感度的丧失。(C)2002年,Elsevier Science Inc. All rights reserved.
PURPOSE: To compare the higher order aberrations of the oculus (whole eye) and cornea in eyes with mild cortical or nuclear cataract and to estimate the effect of ocular higher order aberrations on the loss of contrast sensitivity using wavefront analysis.DESIGN: Observational case series.METHODS: Six eyes of four patients with mild nuclear cataract, 18 eyes of 14 patients with mild cortical cataract, and nine eyes of nine normal patients were examined. Wavefront aberrations of the oculus and cornea for central 6 mm. diameter were measured using the Hartmann-Shack (HS) aberrometer. Higher,order aberrations were calculated with Zernike polynomials up to sixth order. The relationship between average lens density (ALD) measured by the Scheimpflug camera and the ocular total higher-order aberration (OTHA) was investigated. The relationship between contrast sensitivity (CS) and the OTHA or ALD was also examined.RESULTS: The OTHA was significantly larger in cataracts compared with normal subjects, while corneal total higher order aberration did not differ between cataracts and normal subjects. The polarity of spherical aberration was negative in all eyes with nuclear cataract while positive in all eyes with cortical cataract. The correlation between ALD and OTHA was not significant in eyes with cataracts. The CS highly correlated with OTHA while it moderately correlated with ALD.CONCLUSIONS: The HS aberrometer is useful to objectively evaluate the deterioration of images in eyes with mild cataract and it revealed that the polarity of spherical aberration was different between nuclear and cortical cataract. It was also suggested that in mild nuclear or cortical cataract, not only light scattering, but also optical aberration of the lens contributes to the loss of contrast sensitivity. (C) 2002 by Elsevier Science Inc. All rights reserved.