Special issue: molecular and cellular biology of helminth parasites XI.

Special issue: molecular and cellular biology of helminth parasites XI.
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特刊:蠕虫寄生虫的分子和细胞生物学 XI。

DOI:
10.1016/j.ijpara.2018.03.001
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发表时间:
2018
影响因子:
4
通讯作者:
Maizels,RickM
Maizels,RickM
中科院分区:
医学2区
文献类型:
--
作者:
Selkirk,MurrayE;Davis,RichardE;Gounaris,Kleoniki;Maizels,RickM

文献摘要

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蠕虫寄生虫的分子和细胞生物学系列会议于1997年在爱丁堡发起,但自2002年以来一直在希腊的九头蛇岛举行,现在是一年一度的活动,展示了蠕虫全面研究的最新发展。该会议为讨论和协作提供了一个定期的联络点,鉴于该领域的快速发展,这一点尤为重要。2017年的会议也不例外,由克劳斯·布雷姆(德国维尔茨堡大学)的主旨演讲拉开了序幕,他做了一个富有启发性的演讲,采用多学科的方法来说明体细胞是如何驱动多房棘球绦虫的类癌增殖的。随后举行了12次专题会议,涵盖发育生物学、新陈代谢和药物开发、媒介免疫和秀丽隐杆线虫等模式生物的免疫以及免疫调节和发病机制背后的大量宿主-寄生虫分子相互作用等领域。基因组、转录组和蛋白质组信息的开发以及新技术的应用正在带来新一代治疗方法,并揭示了这些非凡生物复杂的适应能力。一如既往,会议在Bratsera酒店举行,尽管今年的海报会议计划在九头蛇博物馆(如图)的屋顶露台举行。还为来自流行国家的早期职业研究人员提供了旅行奖学金,使新的科学家群体更容易参加会议,并使会议具有不同的层面。对代表人数的限制使每一位与会者都有机会在轻松的气氛中通过全体会议或海报会议介绍他们的工作,我们要感谢大家使会议如此成功。
The conference series Molecular and Cellular Biology of Helminth Parasites was initiated in Edinburgh in 1997, but since 2002 has been held on the Greek island of Hydra, and is now an annual event which features the latest developments across the full range of research on helminths. The conference provides a regular focal point for discussion and collaboration, particularly important given the rapid advancements in the field. The 2017 conference was no exception, and was opened by a keynote lecture from Klaus Brehm (University of Würzburg, Germany), who gave an illuminating presentation, employing a multidisciplinary approach to illustrate how the cancer-like proliferation of the Echinococcus multilocularis metacestode is driven by somatic stem cells. Twelve thematic sessions followed, covering areas as diverse as developmental biology, metabolism and drug development, immunity in vectors and model organisms such as Caenorhabditis elegans, and a plethora of host-parasite molecular interactions underlying immunomodulation and pathogenesis. Exploitation of genomic, transcriptomic and proteomic information, and application of new technologies are bringing a new generation of therapeutic approaches, and revealing much more about the intricate adaptations of these remarkable organisms.As always, the conference was held at the Bratsera Hotel, although this year poster sessions were scheduled on the roof-top terrace of the Museum of Hydra (pictured). Travel bursaries for early career researchers from endemic countries were also introduced, making the meeting more accessible to a new group of scientists and giving a different dimension to the meeting. Limitation on delegate numbers allowed every participant the opportunity to present their work either via a plenary talk or poster session in a relaxed atmosphere, and we would like to thank everyone for making the meeting such a success.