The Neurobiological Underpinnings of Coping With Pain
The Neurobiological Underpinnings of Coping With Pain
复制标题
DOI：
10.1111/j.1467-8721.2009.01643.x
复制
发表时间：
2009-08-01
影响因子：
7.2
通讯作者：
Wiech, Katja
中科院分区：
文献类型：
--
作者：
Edwards, Robert R.;Campbell, Claudia;Wiech, Katja
生物心理社会模型将疼痛视为生物，心理和社会因素复杂相互作用的结果。个体在处理疼痛相关症状的方法上的差异是疼痛相关结果的重要决定因素，通常被归类为生物心理社会模型中的“心理”类别。然而，参与各种认知，情感和行为的疼痛应对策略似乎发挥生物学效应，我们在这里审查。疼痛应对活动，如灾难化，分散自己对疼痛感觉的注意力，或重新评估疼痛，可能会影响大脑内各种疼痛处理和疼痛调节回路的活动，以及影响神经肌肉，免疫和神经内分泌系统的功能。疼痛相关的神经生物学和使用特定的疼痛应对技术之间的接口代表了未来疼痛研究的重要途径。
The biopsychosocial model treats pain as resulting from a complex interaction of biological, psychological, and social factors. Individual differences in approaches to coping with pain-related symptoms are important determinants of pain-related outcomes, and are often classified under the "psychological" category within the biopsychosocial model. However, engagement in various cognitive, affective, and behavioral pain-coping strategies appears to exert biological effects, which we review here. Pain-coping activities such as catastrophizing, distracting oneself from pain sensations, or reappraisal of pain may exert effects on activity in a variety of pain-processing and pain-modulatory circuits within the brain, as well affect the functioning of neuromuscular, immune, and neuroendocrine systems. The interface between pain-related neurobiology and the use of specific pain-coping techniques represents an important avenue for future pain research.