Thiomycalolides:: New cytotoxic trisoxazole-containing macrolides isolated from a marine sponge Mycale sp.
Thiomycalolides:: New cytotoxic trisoxazole-containing macrolides isolated from a marine sponge Mycale sp.
复制标题
DOI：
10.1021/np9704866
复制
发表时间：
1998-05-01
影响因子：
5.1
通讯作者：
Fusetani, N
中科院分区：
文献类型：
--
作者：
Matsunaga, S;Nogata, Y;Fusetani, N
Two new cytotoxic trisoxazole macrolides, thiomycalolides A (2) and B (3), have been isolated from a marine sponge Mycale sp. The structures were determined to be glutathione adducts of mycalolides A and B by interpretation of spectral data and chemical transformation. Thiomycalolides A and B are highly cytotoxic against P388 murine leukemia cells.
